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lafutidine
Known as:
(+-)-2-(Furfurylsulfinyl)-N-((Z)-4-((4-(piperidinomethyl)-2-pyridyl)oxy)-2-butenyl) Acetamide
, N-(4-(4-piperidinylmethyl)pyridyl-2-oxy)-(Z)-butenyl-2-(furfurylsulfinyl)acetamide
, N-(4-(4-piperidinylmethyl)pyridyl-2-oxy)butenyl-2-(furfurylsulfinyl)acetamide
National Institutes of Health
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Related topics
Related topics
6 relations
Broader (5)
Acetamides
Anti-Ulcer Agent
Histamine H2 Antagonists
Piperidines
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Narrower (1)
FRG-8813
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Effects of a novel histamine H2‐receptor antagonist, lafutidine, on the mucus barrier of human gastric mucosa
T. Ichikawa
,
H. Ota
,
+4 authors
K. Ishihara
Journal of Gastroenterology and Hepatology
2007
Corpus ID: 24689410
Background and Aim: Lafutidine is a novel histamine H2‐receptor antagonist used primarily as an antisecretory agent in Japan…
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2006
2006
Histamine-induced vasodilation and vasoconstriction in the mesenteric resistance artery of the rat.
Honghua Jin
,
T. Koyama
,
Y. Hatanaka
,
S. Akiyama
,
F. Takayama
,
H. Kawasaki
European Journal of Pharmacology
2006
Corpus ID: 30115696
2006
2006
Lafutidine, a Newly Developed Antiulcer Drug, Elevates Postprandial Intragastric pH and Increases Plasma Calcitonin Gene-Related Peptide and Somatostatin Concentrations in Humans: Comparisons with…
T. Shimatani
,
M. Inoue
,
+5 authors
N. Morikawa
Digestive Diseases and Sciences
2006
Corpus ID: 22678952
Lafutidine, a newly developed histamine H2-receptor antagonist, inhibits daytime (i.e., postprandial) as well as nighttime…
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2005
2005
Early effects of lafutidine or rabeprazole on intragastric acidity: which drug is more suitable for on-demand use?
M. Inamori
,
J. Togawa
,
+15 authors
A. Nakajima
Journal of gastroenterology
2005
Corpus ID: 24648545
BackgroundMedication for the relief of heartburn should have the rapid onset of action required for on-demand use. We studied the…
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2005
2005
Determination of lafutidine in human plasma by high-performance liquid chromatography-electrospray ionization mass spectrometry: application to a bioequivalence study.
Lili Wu
,
Zunjian Zhang
,
+4 authors
Huilin Wei
Journal of Mass Spectrometry
2005
Corpus ID: 11732794
A rapid, sensitive and specific high-performance liquid chromatography-electrospray ionization mass spectrometry (LC/ESI-MS…
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2003
2003
Modifications of capsaicin-sensitive neurons in isolated guinea pig ileum by [6]-gingerol and lafutidine.
Akiyoshi Someya
,
S. Horie
,
Hisashi Yamamoto
,
T. Murayama
Journal of Pharmacological Sciences
2003
Corpus ID: 6775427
A segment of guinea pig ileum was used to confirm the hypothesis that [6]-gingerol and lafutidine interact with capsaicin…
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2003
2003
Lafutidine, a Novel Histamine H2‐Receptor Antagonist, vs. Lansoprazole in Combination with Amoxicillin and Clarithromycin for Eradication of Helicobacter pylori
H. Isomoto
,
Ken-ichiro Inoue
,
+7 authors
S. Kohno
Helicobacter
2003
Corpus ID: 46334193
Background. In contrast to the growing amount of data concerning proton pump inhibitor‐based triple therapy for Helicobacter…
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2001
2001
Effects of vanilloid receptor agonists and antagonists on gastric antral ulcers in rats.
H. Yamamoto
,
S. Horie
,
M. Uchida
,
S. Tsuchiya
,
T. Murayama
,
K. Watanabe
European Journal of Pharmacology
2001
Corpus ID: 31118910
1999
1999
Gastroprotective Mechanism of Lafutidine, a Novel Anti-ulcer Drug with Histamine H2-Receptor Antagonistic Activity
S. Onodera
,
M. Shibata
,
+5 authors
T. Yamaura
Arzneimittelforschung
1999
Corpus ID: 23319777
Summary Lafutidine (CAS 118288-08-7, FRG-8813) is a novel histamine H2-receptor antagonist with gastroprotective activity. The…
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1999
1999
Antiulcer effect of lafutidine on indomethacin-induced gastric antral ulcers in refed rats.
S. Onodera
,
M. Tanaka
,
+6 authors
Y. Sekine
Japanese Journal of Pharmacology
1999
Corpus ID: 21394035
Lafutidine is a new type antiulcer agent with antisecretory and gastroprotective activities. We investigated the effect of…
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