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FRG-8813

Known as: FRG 8813 
National Institutes of Health

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lafutidine

Papers overview

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2000
2000
Effect of FRG-8813, a New-Type Histamine H2-Receptor Antagonist, on the Recurrence of Gastric Ulcer after Healing by Drug Treatment in Rats
We investigated the recurrence of ulcers in rats after treatment with FRG-8813, (±)-2-(furfurylsulfinyl)-N-[4- [4… 
1999
1999
Gastroprotective mechanism of lafutidine, a novel anti-ulcer drug with histamine H2-receptor antagonistic activity.
Lafutidine (CAS 118288-08-7, FRG-8813) is a novel histamine H2-receptor antagonist with gastroprotective activity. The aim of… 
1998
1998
Lafutidine-induced stimulation of mucin biosynthesis mediated by nitric oxide is limited to the surface mucous cells of rat gastric oxyntic mucosa.
Highly Cited
1995
Highly Cited
1995
Gastroprotective activity of FRG-8813, a novel histamine H2-receptor antagonist, in rats.
FRG-8813 ((+/-)-2-(furfurylsulfinyl)-N-[4-[4-(piperidinomethyl)-2- pyridyl]oxy-(Z)-2-butenyl]acetamide) is a novel histamine H2… 
1995
1995
[Studies on histamine H2-receptor antagonistic property of FRG-8813, a novel anti-ulcer drug].
The present study was conducted to investigate the histamine H2-receptor antagonistic property of FRG-8813 by using isolated… 
1995
1995
[Effect of FRG-8813, a new histamine H2-receptor antagonist, on gastric mucus production in rats].
We examined the effect of FRG-8813, a new histamine H2-receptor antagonist, on 1% NH3-induced gastric mucosal lesions and basal… 
1994
1994
Effects of acid-inhibitory antiulcer drugs on mucin biosynthesis in the rat stomach.
Highly Cited
1993
Highly Cited
1993
Gastric antisecretory effect of FRG-8813, a new histamine H2 receptor antagonist, in rats and dogs.
1992
1992
[Effects of FRG-8813, a new-type histamine H2-receptor antagonist, on the healing of gastric and duodenal ulcer in rats and spontaneously ulcerative mice].
We examined the anti-ulcer effects of FRG-8813, a new-type histamine H2-receptor antagonist, in chronic ulcer models of rats and… 
1992
1992
[Effects of FRG-8813, a new type histamine H2-receptor antagonist, on various experimental gastric and duodenal lesions in rats].
We examined the anti-ulcer effects of FRG-8813, a new type histamine H2-receptor antagonist, on various experimental gastric and… 
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