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interleukin-1 secretion

Known as: IL-1 secretion 
The regulated release of interleukin-1 from a cell. Interleukin 1 is produced mainly by activated macrophages; it stimulates thymocyte proliferation… 
National Institutes of Health

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interleukin-1 production

Papers overview

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Highly Cited
2018
Highly Cited
2018
The Pore‐Forming Protein Gasdermin D Regulates Interleukin‐1 Secretion from Living Macrophages
Highly Cited
2013
Highly Cited
2013
Acidosis Drives Damage-associated Molecular Pattern (DAMP)-induced Interleukin-1 Secretion via a Caspase-1-independent Pathway*
Background: IL-1β is a “master” proinflammatory cytokine central to host responses to injury and infection. Danger molecules… 
2008
2008
Functional heterogeneity of rat liver macrophages: interleukin-1 secretion and Ia antigen expression in contrast with phagocytic activity.
To clarify whether immunological heterogeneity exists among liver macrophages and whether this possible heterogeneity corresponds… 
Highly Cited
1994
Highly Cited
1994
Bacterial heat shock proteins directly induce cytokine mRNA and interleukin-1 secretion in macrophage cultures
Bacterial heat shock proteins (hsp) have been shown to be important immunogens stimulating both T cells and B cells. However… 
Highly Cited
1990
Highly Cited
1990
Ex vivo lipopolysaccharide‐induced interleukiri‐1 secretion from murine peritoneal macrophages inhibited by probucol, a hypocholesterolemic agent with antioxidant properties
Probucol, 4,4'‐(isopropylidenedithio)bis(2,6‐di‐tert‐butylphenol), has been shown to inhibit atherogenesis in genetically… 
Highly Cited
1989
Highly Cited
1989
ENDOTHELIAL CELL ACTIVATION AND HIGH INTERLEUKIN-1 SECRETION IN THE PATHOGENESIS OF ACUTE KAWASAKI DISEASE
Highly Cited
1989
Highly Cited
1989
Tumor Necrosis Factor/Cachectin and Interleukin-1 Secretion by Cord Blood Monocytes from Premature and Term Neonates
ABSTRACT: Blood monocytes produce two well-defined cytokines, tumor necrosis factor/cachenterin (TNF) and 11-1, that have… 
Highly Cited
1989
Highly Cited
1989
Phagocytosis of particulate antigens by corneal epithelial cells stimulates interleukin-1 secretion and migration of Langerhans cells into the central cornea.
Under normal physiological conditions, the central corneal epithelium is devoid of Ia+ Langerhans cells. However, a variety of… 
Highly Cited
1986
Highly Cited
1986
Human Monocyte Production of Interleukin‐1: Parameters of the Induction of Interleukin‐1 Secretion by Lipopolysaccharides
  • R. Newton
  • Journal of Leukocyte Biology
  • 1986
  • Corpus ID: 11018872
The role of lipopolysaccharide (LPS) as an activator of human monocyte interleukin‐1 (IL‐1) synthesis and secretion has been… 
Highly Cited
1986
Highly Cited
1986
Physiological mechanisms contributing to increased interleukin-1 secretion.
Interleukin-1 (IL-1) is a monocyte-derived polypeptide that mediates many host defense adaptations to environmental and… 
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