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interleukin-1 secretion

Known as: IL-1 secretion 
The regulated release of interleukin-1 from a cell. Interleukin 1 is produced mainly by activated macrophages; it stimulates thymocyte proliferation… Expand
National Institutes of Health

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interleukin-1 production

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Highly Cited
2018
Highly Cited
2018
The Pore‐Forming Protein Gasdermin D Regulates Interleukin‐1 Secretion from Living Macrophages
Summary The interleukin‐1 (IL‐1) family cytokines are cytosolic proteins that exhibit inflammatory activity upon release into the… Expand
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2013
2013
Acidosis Drives Damage-associated Molecular Pattern (DAMP)-induced Interleukin-1 Secretion via a Caspase-1-independent Pathway*
Background: IL-1β is a “master” proinflammatory cytokine central to host responses to injury and infection. Danger molecules… Expand
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Highly Cited
1994
Highly Cited
1994
Bacterial heat shock proteins directly induce cytokine mRNA and interleukin-1 secretion in macrophage cultures.
Bacterial heat shock proteins (hsp) have been shown to be important immunogens stimulating both T cells and B cells. However… Expand
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1990
1990
Ex vivo lipopolysaccharide-induced interleukin-1 secretion from murine peritoneal macrophages inhibited by probucol, a hypocholesterolemic agent with antioxidant properties.
Probucol, 4,4'-(isopropylidenedithio)bis(2,6-di-tert-butyl-phenol), has been shown to inhibit atherogenesis in genetically… Expand
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Highly Cited
1989
Highly Cited
1989
ENDOTHELIAL CELL ACTIVATION AND HIGH INTERLEUKIN-1 SECRETION IN THE PATHOGENESIS OF ACUTE KAWASAKI DISEASE
To investigate the pathogenesis of Kawasaki disease, the effects of intravenous gammaglobulin treatment on circulating cytotoxic… Expand
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Highly Cited
1989
Highly Cited
1989
Tumor Necrosis Factor/Cachectin and Interleukin-1 Secretion by Cord Blood Monocytes from Premature and Term Neonates
ABSTRACT: Blood monocytes produce two well-defined cytokines, tumor necrosis factor/cachenterin (TNF) and 11-1, that have… Expand
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Highly Cited
1989
Highly Cited
1989
Phagocytosis of particulate antigens by corneal epithelial cells stimulates interleukin-1 secretion and migration of Langerhans cells into the central cornea.
Under normal physiological conditions, the central corneal epithelium is devoid of Ia+ Langerhans cells. However, a variety of… Expand
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Highly Cited
1986
Highly Cited
1986
Physiological mechanisms contributing to increased interleukin-1 secretion.
Interleukin-1 (IL-1) is a monocyte-derived polypeptide that mediates many host defense adaptations to environmental and… Expand
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1986
1986
Human monocyte production of interleukin-1: parameters of the induction of interleukin-1 secretion by lipopolysaccharides.
The role of lipopolysaccharide (LPS) as an activator of human monocyte interleukin-1 (IL-1) synthesis and secretion has been… Expand
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1984
1984
Correlation between strong adjuvanticity of Klebsiella O3 lipopolysaccharide and its ability to induce interleukin-1 secretion.
Adjuvant activity of Klebsiella O3 lipopolysaccharide (KO3 LPS) in augmenting antibody response and delayed-type hypersensitivity… Expand
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