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Evolving functions of endothelial cells in inflammation
TLDR
This Review describes the functions performed by endothelial cells at each stage of the inflammatory process, emphasizing the principal mediators and signalling pathways involved and the therapeutic implications. Expand
Dicer Dependent MicroRNAs Regulate Gene Expression and Functions in Human Endothelial Cells
TLDR
Results indicate that maintenance and regulation of endogenous miRNA levels via Dicer mediated processing is critical for EC gene expression and functions in vitro. Expand
Identification of an inducible endothelial-leukocyte adhesion molecule.
The accumulation of blood leukocytes at sites of inflammation depends upon their localized adhesion to the vascular lining. We have investigated the hypothesis that this adhesive interaction involvesExpand
Selective inhibition of NF-κB activation by a peptide that blocks the interaction of NEMO with the IκB kinase complex
TLDR
The NEMO-binding domain provides a target for the development of drugs that would block proinflammatory activation of the IKK complex without inhibiting basal NF-κB activity. Expand
Cytokines and endothelial cell biology.
TLDR
Ce travail resume les etudes qui ont permi la caracterisation de l'action specifique des cytokines sur les cellules endotheliales dans des cas pathologiques cites dans cet expose. Expand
Tumor necrosis factor receptor-associated factors (TRAFs)
Tumor necrosis factor receptor-associated factors (TRAFS) were initially discovered as adaptor proteins that couple the tumor necrosis factor receptor family to signaling pathways. More recently theyExpand
Tissue-engineered vascular grafts transform into mature blood vessels via an inflammation-mediated process of vascular remodeling
TLDR
Findings suggest TEVGs transform into functional neovessels via an inflammatory process of vascular remodeling in mice implanted with human BMC-seeded scaffolds. Expand
Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis
TLDR
Reduction of endothelial miRNAs by cell-specific inactivation of Dicer reduces postnatal angiogenic response to a variety of stimuli, including exogenous VEGF, tumors, limb ischemia, and wound healing. Expand
Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex.
TLDR
The NBD provides a target for the development of drugs that would block proinflammatory activation of the IKK complex without inhibiting basal NF-kappaB activity. Expand
Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon.
We have used the quantitative binding of murine monoclonal antibodies to the surface of cultured human umbilical vein endothelial (HUVE) cells to study the responses of HUVE cells to three differentExpand
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