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The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells.
TLDR
It is concluded that the synthesis ofIL-1 beta, IL-1 alpha, and tumor necrosis factor can be suppressed by dietary supplementation with long-chain n-3 fatty acids. Expand
Acute phase response in exercise. III. Neutrophil and IL-1 beta accumulation in skeletal muscle.
TLDR
After eccentric exercise ultrastructural damage to skeletal muscle is associated with neutrophil infiltration and muscle IL-1 beta accumulation and positively correlated to intracellular Z-band damage. Expand
Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1
TLDR
These studies show that TNF (cachectin) is another endogenous pyrogen which, like IL-1 and IFN-alpha, directly stimulate hypothalamic PGE2 synthesis and is an endogenous inducer ofIL-1. Expand
Rheumatoid cachexia: cytokine-driven hypermetabolism accompanying reduced body cell mass in chronic inflammation.
TLDR
Loss of body cell mass is common in RA; cytokine production in RA is associated with altered energy metabolism and intake, despite a theoretically adequate diet; and TNF-alpha and IL-1 beta modulate energy metabolic and body composition in RA. Expand
Effect of vitamin E and eccentric exercise on selected biomarkers of oxidative stress in young and elderly men.
TLDR
Vitamin E supplementation induced modest changes eccentric exercise-induced oxidative stress, although differentially between the young and older subjects, while age had no direct influence on these responses among this group of physically fit subjects. Expand
Vitamin E supplementation enhances cell-mediated immunity in healthy elderly subjects.
TLDR
Short-term vitamin E supplementation improves immune responsiveness in healthy elderly individuals; this effect appears to be mediated by a decrease in PGE2 and/or other lipid-peroxidation products. Expand
Circulating interleukin-1 and tumor necrosis factor in septic shock and experimental endotoxin fever.
TLDR
The concept that plasma IL-1 beta and TNF-alpha concentrations are regulated independently and are associated with different clinical outcomes is supported. Expand
Metabolic changes following eccentric exercise in trained and untrained men.
TLDR
Regularly performed long distance running was associated with chronically elevated plasma IL-1 levels and serum CK activities without acute increases after an eccentric exercise bout, suggesting that in untrained men eccentric exercise leads to a metabolic response indicative of delayed muscle damage. Expand
Acute phase response in exercise. II. Associations between vitamin E, cytokines, and muscle proteolysis.
TLDR
Urinary 3-methylhistidine excretion correlated with mononuclear cell secretion of both IL-1 beta and prostaglandin E2, supporting the concept that these mon onuclear cell products contribute to the regulation of muscle proteolysis. Expand
Acute phase response in exercise: interaction of age and vitamin E on neutrophils and muscle enzyme release.
TLDR
The association of enzyme efflux with neutrophil mobilization and function supports the concept that neutrophils are involved in the delayed increase in muscle membrane permeability after damaging exercise. Expand
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