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IL-33 and ST2 in atopic dermatitis: expression profiles and modulation by triggering factors.
Increased expression of IL-33 and ST2 in AD skin after allergen or staphylococcal enterotoxin B (SEB) exposure is found as well as in the skin of 22-week-old filaggrin-deficient mice, suggesting an important role for IL- 33-ST2 interaction in AD and highlighting the fact that bacterial and viral infections may increase the production ofIL-33. Expand
A novel wheat gliadin as a cause of exercise-induced anaphylaxis.
It is shown that wheat is a frequent cause of food-dependent, exercise-induced anaphylaxis and suggests that the major allergen is a previously undescribed gamma-like gliadin, while a gluten-free or wheat-free diet is recommended for treatment. Expand
Coeliac disease--associated disorders and survival.
At least 83% of the coeliac patients adhered strictly to the gluten free diet, which may explain the favourable outcome, and the five year survival rates of coeliasis patients did not differ from those in the general population. Expand
Immunoglobulin A autoantibodies against transglutaminase 2 in the small intestinal mucosa predict forthcoming coeliac disease
Coeliac autoantibodies in the serum or Marsh I inflammation may be indicators of subsequent coeliac disease. Expand
Natural rubber latex allergy
It has recently been emphasized that NRL allergens become easily airborne with glove powder and that persons sensitized to NRL may also suffer from occupational asthma and the presence of specific IgE in NRL-allergic patients may be verified by skin prick tests (SPT) or by serologic methods such as RAST. Expand
Selective IgA deficiency and coeliac disease.
Patients with selective IgA deficiency have at least a tenfold risk of coeliac disease compared with the population in general and have other concomitant diseases, especially autoimmune diseases. Expand
Endomysial antibody-negative coeliac disease: clinical characteristics and intestinal autoantibody deposits
Background: Some patients with untreated coeliac disease are negative for serum endomysial autoantibodies (EmA) targeted against transglutaminase 2 (TG2). Aims: To evaluate the clinical andExpand
High incidence and prevalence of adult coeliac disease. Augmented diagnostic approach.
The aim was to detect coeliac disease patients with such atypical or no symptoms as well as those with typical features, and gave a coeliasis prevalence similar to that found in population screening studies. Expand
Autoimmune thyroid disorders and coeliac disease.
The present results confirm that the frequency of subclinical coeliac disease is increased among patients with autoimmune thyroid disorders, and IgA-class reticulin, endomysium or gliadin antibody tests are suitable screening methods for detecting these patients. Expand
Wheat ω-5 gliadin is a major allergen in children with immediate allergy to ingested wheat☆☆☆
The results of this study show that ω-5 gliadin is a significant allergen in young children with immediate allergic reactions to ingested wheat and could be used to reduce the need for oral wheat challenges in children. Expand