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inositol trisphosphate biosynthetic process

Known as: inositol trisphosphate anabolism, inositol trisphosphate biosynthesis, IP3 biosynthetic process 
The chemical reactions and pathways resulting in the formation of inositol trisphosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups… 
National Institutes of Health

Related topics

Related topics

1 relation
negative regulation of inositol trisphosphate biosynthetic process

Papers overview

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Highly Cited
1998
Highly Cited
1998
Selective ceramide binding to protein kinase C-alpha and -delta isoenzymes in renal mesangial cells.
Ceramide is an important lipid second messenger produced by sphingolipid metabolism in cells exposed to a limited number of… 
Highly Cited
1996
Highly Cited
1996
Effects of nicotine on the immune response. II. Chronic nicotine treatment induces T cell anergy.
Previously, we have shown that both T and B lymphocytes from chronically nicotine-treated (NT) animals exhibit tolerance to… 
Highly Cited
1991
Highly Cited
1991
Cloning by functional expression of platelet-activating factor receptor from guinea-pig lung
PLATELET-activating factor (PAF), a unique phospholipid mediator, possesses potent proinflammatory, smooth-muscle contractile and… 
Highly Cited
1989
Highly Cited
1989
Effect of esters of succinic acid and other citric acid cycle intermediates on insulin release and inositol phosphate formation by pancreatic islets.
Highly Cited
1988
Highly Cited
1988
Guanine nucleotides stimulate polyphosphoinositide phosphodiesterase and exocytotic secretion from HL60 cells permeabilized with streptolysin O.
The non-differentiated HL60 cell can be stimulated to secrete when Ca2+ and guanosine 5'-[gamma-thio]-triphosphate (GTP gamma S… 
Highly Cited
1987
Highly Cited
1987
Guanosine 5'-O-(thiotriphosphate)-dependent inositol trisphosphate formation in membranes is inhibited by phorbol ester and protein kinase C.
Highly Cited
1986
Highly Cited
1986
Thyrotropin-releasing hormone and GTP activate inositol trisphosphate formation in membranes isolated from rat pituitary cells.
Stimulation of the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) by a phospholipase C to produce inositol… 
Highly Cited
1985
Highly Cited
1985
5-Hydroxytryptamine stimulates inositol phosphate production in a cell-free system from blowfly salivary glands. Evidence for a role of GTP in coupling receptor activation to phosphoinositide…
Highly Cited
1985
Highly Cited
1985
Stimulation of inositol trisphosphate formation in hepatocytes by vasopressin, adrenaline and angiotensin II and its relationship to changes in cytosolic free Ca2+.
At maximally effective concentrations, vasopressin (10(-7) M) increased myo-inositol trisphosphate (IP3) in isolated rat… 
Highly Cited
1985
Highly Cited
1985
Phorbol ester and 1-oleoyl-2-acetylglycerol inhibit angiotensin activation of phospholipase C in cultured vascular smooth muscle cells.
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