FAQ

indolactam V

Known as: 3H-Pyrrolo(4,3,2-gh)-1,4-benzodiazonin-3-one, 1,2,4,5,6,8-hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-, (2S-(2R*,5R*))-, indolactam-V 
 

Topic mentions per year

Topic mentions per year

1991-2018
012319912018

Related topics

Related topics

3 relations

Broader (3)

CarcinogensIndolesLactams

Related mentions per year

Related mentions per year

1939-2018
19401960198020002020
indolactam V
Carcinogens
Lactams
Indoles

Papers overview

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2014
2014
Total syntheses of indolactam alkaloids (-)-indolactam V, (-)-pendolmycin, (-)-lyngbyatoxin A, and (-)-teleocidin A-2.
We report the total syntheses of (-)-indolactam V and the C7-substituted indolactam alkaloids (-)-pendolmycin, (-)-lyngbyatoxin A… (More)
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2011
2011
Indolactam V/GLP-1-mediated Differentiation of Human iPS Cells into Glucose-Responsive Insulin-Secreting Progeny
Nuclear reprogramming of somatic tissue enables derivation of induced pluripotent stem (iPS) cells from an autologous, non… (More)
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2004
2004
Investigation of G protein-initiated, Ca2+-dependent release of ATP from endothelial cells.
We investigated G protein-stimulated release of ATP from human umbilical vein endothelial cells (HUVECs) using the G protein… (More)
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2001
2001
Morphine inhibits indolactam V-induced U937 cell adhesion and gelatinase secretion.
We demonstrate that indolactam V, a non-phorbol protein kinase C activator, promotes U937 cell attachment to fibronectin, type IV… (More)
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1999
1999
Natural Product Synthesis on Polymeric Supports-Synthesis and Biological Evaluation of an Indolactam Library.
Potent activators of protein kinase C in fibroblasts: This property was determined for several indolactam V analogues (1) with a… (More)
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1998
1998
Temperature and protein kinase C modulate myofilament Ca2+ sensitivity in pressurized rat cerebral arteries.
The effects of pharmacological activation and inhibition of protein kinase C (PKC) and temperature on the relationship between… (More)
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1998
1998
The involvement of novel protein kinase C isozymes in influencing sensitivity of breast cancer MCF-7 cells to tumor necrosis factor-alpha.
Protein kinase C (PKC) has been implicated in tumor necrosis factor-alpha (TNF) signaling. Structurally and functionally distinct… (More)
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1997
1997
Modeling, chemistry, and biology of the benzolactam analogues of indolactam V (ILV). 2. Identification of the binding site of the benzolactams in the CRD2 activator-binding domain of PKCdelta and…
Protein kinase C (PKC) is a complex enzyme system comprised of at least 11 isozymes that serves to mediate numerous extracellular… (More)
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1997
1997
Activation of protein kinase C subtypes alpha, gamma, delta, epsilon, zeta, and eta by tumor-promoting and nontumor-promoting agents.
Protein kinase C (PKC) subtypes alpha, gamma, delta, epsilon, zeta, and eta have been expressed using the baculovirus expression… (More)
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1991
1991
Cellular sensitization to cis-diamminedichloroplatinum(II) by novel analogues of the protein kinase C activator lyngbyatoxin A.
Protein kinase C (PKC) has been implicated in enhancing cellular sensitivity to cis-diamminedichloroplatinum(II) (CP). We have… (More)
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