imidazobenzodiazepine

GABAA receptors (GABARs) have long been the focus for acute alcohol actions with evidence for behaviorally relevant low… Expand

Alcohol (ethanol, EtOH) has pleiotropic actions and induces a number of acute and long-term effects due to direct actions on… Expand

Several structural subclasses of ligands bind to the benzodiazepine (BZD) binding site of the GABA(A) receptor. Previous studies… Expand

Ligands binding to the benzodiazepine-binding site in gamma-aminobutyric acid type A (GABA(A)) receptors may allosterically… Expand

We characterized modulation of the gamma-aminobutyric acid (GABA)-evoked responses of the diazepam-insensitive alpha 4 beta 2… Expand

Ro 15-4513 (ethyl-8-azido-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a] [1,4]benzodiazepine-3-carboxylate), a partial inverse… Expand

Ethanol, at pharmacologically relevant concentrations of 20 to 100 mM, stimulates gamma-aminobutyric (GABA) receptor-mediated… Expand

Midazolam is an imidazobenzodiazepine with unique properties when compared with other benzodiazepines. It is water soluble in its… Expand

Le midazolam est au moins aussi efficace que le diazepam, les malades le preferent en general; il y a moins de complications… Expand

Abstract The imidazobenzodiazepine RO 15-1788 is a specific proconvulsant against isoniazid induced convulsions when given… Expand