igmesine

Known as: cinnamyl-1-phenyl-1-N-methyl-N-cyclopropylene 
 
National Institutes of Health

Papers overview

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2011
2011
The sigma-1 (σ₁) protein regulates calcium homeostasis and acts as an endoplasmic reticulum chaperone. It can be activated by… Expand
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2011
2011
Sigma(1) receptors (σ(1)Rs) represent a structurally unique class of intracellular proteins that function as chaperones. σ(1)Rs… Expand
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2006
2006
In the present study, we examined the interaction of (+/-)-2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]-methyl… Expand
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Review
2004
Review
2004
The sigma receptor was originally proposed to be a subtype of the opioid receptor. However, it is now clear that sigma receptors… Expand
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2004
2004
In utero cocaine (IUC) exposure results in offspring rats in complex neurochemical and behavioral alterations, particularly… Expand
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Review
2004
Review
2004
So far, sigma-ligands have been investigated for several indications in human studies in functional diarrhea as a model of… Expand
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2004
2004
AbstractRationaleCocaine-seeking behavior can be investigated in rodents using the conditioned place preference (CPP) paradigm… Expand
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2003
2003
The sigma1 receptor is critically involved in the rewarding effect of cocaine, as measured using the conditioned place preference… Expand
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Highly Cited
2002
Highly Cited
2002
The involvement of the sigma1 receptor on the rewarding effects of cocaine was examined using the conditioned place preference… Expand
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2001
2001
Igmesine is a selective sigma (sigma(1)) ligand that was reported to exert antidepressant action through an unknown mechanism of… Expand
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