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Colonic Biopsies to Assess the Neuropathology of Parkinson's Disease and Its Relationship with Symptoms
Background The presence of Lewy bodies and Lewy neurites (LN) has been demonstrated in the enteric nervous system (ENS) of Parkinson's disease (PD) patients. The aims of the present research were toExpand
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Outcomes of treatment for achalasia depend on manometric subtype.
BACKGROUND & AIMS Patients with achalasia are treated with either pneumatic dilation (PD) or laparoscopic Heller myotomy (LHM), which have comparable rates of success. We evaluated whether manometricExpand
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Impaired intestinal barrier integrity in the colon of patients with irritable bowel syndrome: involvement of soluble mediators
Background: Growing evidence suggests that patients with irritable bowel syndrome (IBS) have increased intestinal permeability. In addition, mucosal soluble mediators are involved in theExpand
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Parkinson disease
Lewy pathology in Parkinson disease (PD) extends well beyond the CNS, also affecting peripheral autonomic neuronal circuits, especially the enteric nervous system (ENS). The ENS is an integrativeExpand
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Normal values and day‐to‐day variability of 24‐h ambulatory oesophageal impedance‐pH monitoring in a Belgian–French cohort of healthy subjects
Background : Impedance‐pH monitoring is the most sensitive method for detection and characterization of gastro‐oesophageal reflux episodes. Normal values from European subjects are lacking.
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Gastric Electrical Stimulation in Intractable Symptomatic Gastroparesis
Background: The treatment of gastroparesis remains unsatisfactory despite prokinetic and anti-emetic drugs. Gastric electrical stimulation has been proposed as a therapeutic option. We have assessedExpand
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Chemotherapy‐driven dysbiosis in the intestinal microbiome
Chemotherapy is commonly used as myeloablative conditioning treatment to prepare patients for haematopoietic stem cell transplantation (HSCT). Chemotherapy leads to several side effects, withExpand
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Long-term results of the European achalasia trial: a multicentre randomised controlled trial comparing pneumatic dilation versus laparoscopic Heller myotomy
Objective Achalasia is a chronic motility disorder of the oesophagus for which laparoscopic Heller myotomy (LHM) and endoscopic pneumodilation (PD) are the most commonly used treatments. However,Expand
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Systematic review: the role of the gut microbiota in chemotherapy‐ or radiation‐induced gastrointestinal mucositis – current evidence and potential clinical applications
Gastrointestinal mucositis is defined as inflammation and/or ulcers of the gastrointestinal tract occurring as a complication of chemotherapy and radiation therapy, and affects about 50% of allExpand
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Irritable bowel syndrome in France: a common, debilitating and costly disorder
Objective This epidemiological investigation aims to measure the prevalence of irritable bowel syndrome (IBS) in the general population using the Rome II criteria and to evaluate the medicalExpand
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