• Publications
  • Influence
Hyperfunction of Dopaminergic and Serotonergic Neuronal Systems in Mice Lacking the NMDA Receptor ε1 Subunit
NMDA receptors, an ionotropic subtype of glutamate receptors (GluRs) forming high Ca2+-permeable cation channels, are composed by assembly of the GluRζ subunit (NR1) with any one of four GluRεExpand
  • 149
  • 5
The tissue plasminogen activator-plasmin system participates in the rewarding effect of morphine by regulating dopamine release.
Tissue plasminogen activator (tPA) is a serine protease that catalyzes the conversion of plasminogen (plg) to plasmin, which in turn functions to degrade extracellular matrix proteins in the centralExpand
  • 105
  • 5
  • PDF
Chronic DHEAS administration facilitates hippocampal long-term potentiation via an amplification of Src-dependent NMDA receptor signaling
Dehydroepiandrosterone sulfate (DHEAS) has well characterized effects on memory and cognitive performances. Recently we have reported that repetitive administration of DHEAS lowers the thresholdExpand
  • 37
  • 3
Lower sensitivity to stress and altered monoaminergic neuronal function in mice lacking the NMDA receptor epsilon 4 subunit.
NMDA receptors, an ionotropic subtype of glutamate receptors (GluRs), play an important role in excitatory neurotransmission, synaptic plasticity, and brain development. They are composed of theExpand
  • 52
  • 3
ALCAM (CD166) Is a Surface Marker for Early Murine Cardiomyocytes
ALCAM (activated leukocyte cell adhesion molecule, CD166) belongs to the immunoglobulin superfamily and is involved in axon guidance, hematopoiesis, immune response and tumor metastasis. DuringExpand
  • 37
  • 3
Lower Sensitivity to Stress and Altered Monoaminergic Neuronal Function in Mice Lacking the NMDA Receptor ε4 Subunit
NMDA receptors, an ionotropic subtype of glutamate receptors (GluRs), play an important role in excitatory neurotransmission, synaptic plasticity, and brain development. They are composed of theExpand
  • 74
  • 2
The role of tissue plasminogen activator in methamphetamine‐related reward and sensitization
In the central nervous system, tissue plasminogen activator (tPA) plays a role in synaptic plasticity and remodeling. Our recent study has suggested that tPA participates in the rewarding effects ofExpand
  • 49
  • 2
Behavioural adaptations to addictive drugs in mice lacking the NMDA receptor ε1 subunit
N‐methyl‐d‐aspartate (NMDA) receptors, a subtype of glutamate receptors (GluRs) formed by assembly of the GluRζ subunit (called NR1 in rats) with any one of four GluRε subunits (GluRε1–4; NR2A–D),Expand
  • 53
  • 2
Behavioral phenotypes for negative symptoms in animal models of schizophrenia.
A devastating psychiatric disorder, schizophrenia is characterized by three major symptoms, positive and negative symptoms and cognitive deficit. Almost all current therapeutic drugs forExpand
  • 14
  • 2
  • PDF