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idoxifene

Known as: Pyr-I-Tam, 4-iodopyrrolidinotamoxifen, 1-[2-[4-[(1E)-1-(4-Iodophenyl)-2-phenyl-1-butenyl]phenoxy]ethyl]pyrrolidine 
A drug that blocks the effects of estrogen.
National Institutes of Health

Related topics

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3 relations

Broader (2)

Estrogen AntagonistsTamoxifen
analogs & derivatives

Papers overview

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2005
2005
Antiapoptotic mechanisms of idoxifene on cultured rat hepatocytes undergoing oxidative stress
OBJECTIVE To study the effects of the non steroidal estrogen antagonist idoxifene on hepatocyte apoptosis induced by oxidative… 
2004
2004
Effect of idoxifene on the proliferation of osteoblasts and typeIcollagen synthesis in rats
Objective To investigate the effect of idoxifene on the proliferation of osteoblasts and typeⅠcollagen synthesis in culture from… 
2002
2002
Clinical Biomechanics Award 2001 High-resolution MRI and micro-FE for the evaluation of changes in bone mechanical properties during longitudinal clinical trials: application to calcaneal bone in…
Objective. To investigate whether recently developed in vivo high-resolution magnetic resonance-imaging and micro-finite element… 
2001
2001
High-resolution MRI and micro-FE for the evaluation of changes in calcaneal bone mechanical properties in postmenopausal women after one year of idoxifene treatment
Introduction Current methods for the assessment of fracture risk in osteoporosis are primarily based on bone mineral density (BMD… 
2001
2001
Effects of idoxifene and estradiol on NF-κB activation in cultured rat hepatocytes undergoing oxidative stress
2001
2001
A Novel Synthesis of Idoxifene
  • Xu Lin
  • 2001
  • Corpus ID: 101484579
Idoxifene, an estrogen receptor modulator was synthesised from 1 (4 iodophenyl) 2 phenyl 1 butanone (4) with the Grignard reagent… 
2000
2000
Study for the Synthesis of $[^{123}I]$Idoxifene and Its Uptake in the Breast Cancer Cell
Purpose: Idoxifene is currently entering phase II clinical trials for the treatment of advanced breast cancer. The radiolabeled… 
2000
2000
The effect of idoxifene on structural and mechanical properties of bone assessed by non invasive techniques in postmenopausal women
1998
1998
P-56. Idoxifene is Well Tolerated in Osteopenic Postmenopausal Women
1996
1996
Corrigendum: Induction of hepatic aneuploidy in vivo by tamoxifen, toremifene and idoxifene in female Sprague rats (Carcinogenesis (1996) 17 (1051-1056))