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idoxifene

Known as: Pyr-I-Tam, 4-iodopyrrolidinotamoxifen, 1-[2-[4-[(1E)-1-(4-Iodophenyl)-2-phenyl-1-butenyl]phenoxy]ethyl]pyrrolidine 
A drug that blocks the effects of estrogen.
National Institutes of Health

Papers overview

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Review
2001
Review
2001
  • M. Dowsett
  • Endocrine-related cancer
  • 2001
  • Corpus ID: 1510886
Hormonal therapy leads to improved survival in oestrogen receptor (ER) positive early breast cancer and long-term responses in… Expand
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Highly Cited
2001
Highly Cited
2001
In experimental models, human epidermal growth factor receptor-2 (HER-2) amplification leads to estrogen independence and… Expand
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Highly Cited
2001
Highly Cited
2001
PURPOSE Raloxifene is a selective estrogen receptor (ER) modulator approved for prevention and treatment of postmenopausal… Expand
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Highly Cited
2000
Highly Cited
2000
Idoxifene is a novel selective estrogen receptor modulator. It has reduced agonist activity on breast and uterine cells compared… Expand
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Highly Cited
1999
Highly Cited
1999
Antiestrogens such as tamoxifen are one of the most effective methods of treating estrogen receptor (ERa) positive breast cancers… Expand
Highly Cited
1999
Highly Cited
1999
Idoxifene is a novel selective estrogen (E2) receptor (ER) modulator that is currently in clinical development for the treatment… Expand
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Highly Cited
1998
Highly Cited
1998
We have discovered a new, nonsteroidal, potent estrogen agonist/antagonist, CP-336,156. CP-336,156 binds selectively and with… Expand
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Highly Cited
1998
Highly Cited
1998
Idoxifene, a novel selective estrogen receptor modulator, was tested for its effects on bone loss, serum cholesterol, and uterine… Expand
Highly Cited
1995
Highly Cited
1995
Idoxifene, a novel antiestrogen with reduced estrogenic activity when compared to tamoxifen, has been given to 20 women with… Expand
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Highly Cited
1991
Highly Cited
1991
New tamoxifen analogues were tested for their antiproliferative activity both in vitro and in vivo. Binding studies showed that… Expand
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