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idoxifene

Known as: Pyr-I-Tam, 4-iodopyrrolidinotamoxifen, 1-[2-[4-[(1E)-1-(4-Iodophenyl)-2-phenyl-1-butenyl]phenoxy]ethyl]pyrrolidine 
A drug that blocks the effects of estrogen.
National Institutes of Health

Papers overview

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2014
2014
ABSTRACT Cryptococcosis is an infectious disease of global significance for which new therapies are needed. Repurposing… Expand
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Review
2006
Review
2006
The estrogen receptor alpha (ERalpha) has proven to be the single most important target in breast cancer over the last 30 years… Expand
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2004
2004
Oxidative stress plays a causative role in the development of hepatic fibrosis and apoptosis. Estradiol (E2) is an antioxidant… Expand
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2002
2002
OBJECTIVE To investigate whether recently developed in vivo high-resolution magnetic resonance-imaging and micro-finite element… Expand
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Highly Cited
2001
Highly Cited
2001
In experimental models, human epidermal growth factor receptor-2 (HER-2) amplification leads to estrogen independence and… Expand
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Review
2000
Review
2000
Since the description of the first antioestrogen, MER 25, more than four decades ago (Lerner et al. 1958), and of tamoxifen ten… Expand
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2000
2000
Idoxifene is a novel selective estrogen receptor modulator. It has reduced agonist activity on breast and uterine cells compared… Expand
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1999
1999
Idoxifene is a novel selective estrogen (E2) receptor (ER) modulator that is currently in clinical development for the treatment… Expand
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Highly Cited
1999
Highly Cited
1999
Antiestrogens such as tamoxifen are one of the most effective methods of treating estrogen receptor (ERalpha) positive breast… Expand
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1995
1995
Idoxifene, a novel antiestrogen with reduced estrogenic activity when compared to tamoxifen, has been given to 20 women with… Expand
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