ibudilast

Known as: Pyrazolo(1,5-a)pyridine, 3-isobutyryl-2-isopropyl-, Ibudilastum, 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine 
 
National Institutes of Health

Papers overview

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2015
2015
Neuroinflammatory signaling pathways in the central nervous system are of current interest as potential pharmacotherapy targets… (More)
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2010
2010
BACKGROUND Ibudilast is a phosphodiesterase inhibitor influencing inflammation and neurodegeneration in multiple sclerosis (MS… (More)
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2010
2010
AV411 (ibudilast; 3-isobutyryl-2-isopropylpyrazolo-[1,5-a]pyridine) is an antiinflammatory drug that was initially developed for… (More)
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2010
2010
OBJECTIVE Phosphodiesterase-4 (PDE-4) is a cyclic adenosine monophosphate-specific enzyme involved in various inflammatory… (More)
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Highly Cited
2009
Highly Cited
2009
Morphine-induced glial proinflammatory responses have been documented to contribute to tolerance to opioid analgesia. Here, we… (More)
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2009
2009
BACKGROUND Opioid analgesics are effective in relieving chronic pain, but they have serious adverse effects, including… (More)
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2008
2008
AIMS To investigate the safety, tolerability and pharmacokinetics (PK) of ibudilast after a single-dose and a multiple-dose… (More)
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Review
2007
Review
2007
The treatment of neuropathic pain is a major unresolved medical challenge. Present pharmacotherapies only have modest efficacy… (More)
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2003
2003
Cerebrovascular white matter (WM) lesions, which are frequently observed in vascular cognitive impairment and vascular dementia… (More)
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1992
1992
Ibudilast, a unique agent with vasodilating and antiallergic actions, was studied in 13 asthmatics for its effect on airway… (More)
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