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ibudilast

Known as: Pyrazolo(1,5-a)pyridine, 3-isobutyryl-2-isopropyl-, Ibudilastum, 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine 
National Institutes of Health

Papers overview

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Highly Cited
2018
Highly Cited
2018
BACKGROUND There are limited treatments for progressive multiple sclerosis. Ibudilast inhibits several cyclic nucleotide… Expand
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Highly Cited
2017
Highly Cited
2017
Current directions in medication development for alcohol use disorder (AUD) emphasize the need to identify novel molecular… Expand
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Highly Cited
2015
Highly Cited
2015
Neuroinflammatory signaling pathways in the central nervous system are of current interest as potential pharmacotherapy targets… Expand
Highly Cited
2010
Highly Cited
2010
Background: Ibudilast is a phosphodiesterase inhibitor influencing inflammation and neurodegeneration in multiple sclerosis (MS… Expand
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Highly Cited
2010
Highly Cited
2010
AV411 (ibudilast; 3-isobutyryl-2-isopropylpyrazolo-[1,5-a]pyridine) is an antiinflammatory drug that was initially developed for… Expand
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Highly Cited
2009
Highly Cited
2009
Morphine-induced glial proinflammatory responses have been documented to contribute to tolerance to opioid analgesia. Here, we… Expand
Review
2009
Review
2009
Ibudilast is a relatively nonselective phosphodiesterase inhibitor which has been marketed for almost 20 years in Japan for… Expand
Review
2007
Review
2007
The treatment of neuropathic pain is a major unresolved medical challenge. Present pharmacotherapies only have modest efficacy… Expand
Highly Cited
2004
Highly Cited
2004
The phosphodiesterase inhibitor, ibudilast, has many effects on lymphocytes, endothelial cells, and glial cells. We examined the… Expand
Highly Cited
1999
Highly Cited
1999
Tumor necrosis factor alpha (TNFalpha) is considered to play a critical role in the development of various pathological processes… Expand