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ibudilast

Known as: Pyrazolo(1,5-a)pyridine, 3-isobutyryl-2-isopropyl-, Ibudilastum, 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine 
National Institutes of Health

Related topics

Related topics

10 relations

Narrower (5)

AV-411EyevinalKC 404Ke tas

Broader (5)

Bronchodilator AgentsPhosphodiesterase InhibitorsPlatelet Aggregation InhibitorsPyridines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Ibudilast reduces alcohol drinking in multiple animal models of alcohol dependence
Neuroinflammatory signaling pathways in the central nervous system are of current interest as potential pharmacotherapy targets… 
Highly Cited
2015
Highly Cited
2015
Cortical neuroinflammation contributes to long-term cognitive dysfunctions following adolescent delta-9-tetrahydrocannabinol treatment in female rats
Review
2014
Review
2014
Neuroinflammatory contributions to pain after SCI: Roles for central glial mechanisms and nociceptor-mediated host defense
Review
2009
Review
2009
Ibudilast: a review of its pharmacology, efficacy and safety in respiratory and neurological disease
Ibudilast is a relatively nonselective phosphodiesterase inhibitor which has been marketed for almost 20 years in Japan for… 
Review
2007
Review
2007
Ibudilast (AV-411)
The treatment of neuropathic pain is a major unresolved medical challenge. Present pharmacotherapies only have modest efficacy… 
2005
2005
Anti-inflammatory therapy by ibudilast, a phosphodiesterase inhibitor, in demyelination of twitcher, a genetic demyelination model
BackgroundTwitcher mouse (twi/twi) is an authentic murine model of Krabbe's disease. Accumulation of psychosine, resulting in… 
Highly Cited
2004
Highly Cited
2004
Neuroprotective role of phosphodiesterase inhibitor ibudilast on neuronal cell death induced by activated microglia
Highly Cited
2004
Highly Cited
2004
Ibudilast, a nonselective phosphodiesterase inhibitor, regulates Th1/Th2 balance and NKT cell subset in multiple sclerosis
We investigated the immunoregulatory effects of ibudilast, a nonselective phosphodiesterase inhibitor, at a clinically applicable… 
2001
2001
Ibudilast attenuates astrocyte apoptosis via cyclic GMP signalling pathway in an in vitro reperfusion model
We examined the effect of 3‐isobutyryl‐2‐isopropylpyrazolo[1,5‐a]pyridine (ibudilast), which has been clinically used for… 
Highly Cited
1992
Highly Cited
1992
Effect of ibudilast: a novel antiasthmatic agent, on airway hypersensitivity in bronchial asthma.
Ibudilast, a unique agent with vasodilating and antiallergic actions, was studied in 13 asthmatics for its effect on airway… 
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