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histrionicotoxin

National Institutes of Health

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Amphibian Venoms

Papers overview

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Review
2007
Review
2007
Thirty-five years of synthetic studies directed towards the histrionicotoxin family of alkaloids.
This article brings together for the first time reviews of all the synthetic attempts towards the spirocyclic histrionicotoxin… 
2002
2002
The total synthesis of alkaloids (-)-histrionicotoxin 259A, 285C and 285E.
The first total syntheses of three "unsymmetrical" (i.e. different terminal groups in the side chains) members of the… 
1986
1986
Voltage- and time-dependent effects of phencyclidines on the endplate current arise from open and closed channel blockade.
The actions of phencyclidine [1-(1-phenylcyclohexyl)piperidine, PCP] and its morpholine analog [1-(1-phenylcyclohexyl)morpholine… 
1986
1986
Enhancement of brain calcium antagonist binding by phencyclidine and related compounds
1981
1981
Functional properties of acetylcholine receptor monomeric and dimeric forms in reconstituted membranes.
Highly Cited
1978
Highly Cited
1978
Distinct protein components from Torpedo marmorata membranes carry the acetylcholine receptor site and the binding site for local anesthetics and histrionicotoxin.
Highly purified subsynaptic membrane fragments prepared from Torpedo marmorata electric organ (specific activity, greater than 4… 
Highly Cited
1978
Highly Cited
1978
Acetylcholine receptor and ionic channel of Torpedo electroplax: binding of perhydrohistrionicotoxin to membrane and solubilized preparations.
The electric organ of the ray, Torpedo ocellata, can serve as a source for both the acetylcholine (ACh) receptor and its ionic… 
1977
1977
Interactions of perhydrohistrionicotoxin with postsynaptic membranes.
Highly Cited
1974
Highly Cited
1974
Allenic and acetylenic spiropiperidine alkaloids from the neotropical frog, Dendrobates histrionicus.
Four analogs of the acetylenic alkaloid, histrionicotoxin (C19H25NO) and the allenic alkaloid, isodihydrohistrionicotoxin have… 
1974
1974
Histrionicotoxin: effects on some central and peripheral excitable cells.
Studies on the rat diaphragm confirmed previous reports that histrionicotoxin (HTX) reversibly blocks contractions, miniature end… 
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