hexamethylene bisacetamide

Known as: N,N'-Hexamethylenebisacetamide, Acetamide, N,N'-hexamethylenebis-, HMBA 
A hybrid polar-planar compound with potential antineoplastic activity that induces terminal differentiation, inhibits cell growth, and causes… (More)
National Institutes of Health

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Highly Cited
1999
Highly Cited
1999
Determinants of differentiation and apoptosis in myelomonocytic leukemia cells (U937) exposed to the novel hybrid polar compound… (More)
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Highly Cited
1998
Highly Cited
1998
Hybrid polar compounds (HPCs) have been synthesized that induce terminal differentiation and/or apoptosis in various transformed… (More)
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1992
1992
Hexamethylene bisacetamide (HMBA) is a potent inducer of differentiation of a number of transformed cell lines in vitro. We… (More)
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1992
1992
Hexamethylene bisacetamide (HMBA) and DMSO are known to induce differentiation of cultured erythroleukaemic cells and to enhance… (More)
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1990
1990
The differentiation agent hexamethylene bisacetamide (HMBA) increased expression of transforming growth factor beta 1 (TGF beta 1… (More)
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1990
1990
The effects of 5-fluorouracil (5-FUra), in combination with various differentiation inducers on the growth and differentiation of… (More)
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1987
1987
Nonthrombocytopenic purpura developed in a patient receiving hexamethylene bisacetamide, a tumor-differentiating agent in vitro… (More)
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1986
1986
Hexamethylene bisacetamide (HMBA, NSC 95580) has been demonstrated to be the most effective of the known and studied polar-planar… (More)
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Highly Cited
1980
Highly Cited
1980
The HL-60 cell line, derived from a patient with acute promyelocytic leukemia, proliferates continuously in suspension culture… (More)
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Highly Cited
1977
Highly Cited
1977
Friend virus-transformed murine erythroleukemia cells express the program of erythropoietic differentiation under the influence… (More)
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