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herbimycin

Known as: 17-Demethoxy-15-methoxy-11-O-methylgeldanamycin, (15R)-, geldanamycin, 17-demethoxy-15-methoxy-11-O-methyl-, (15R)-, Herbimycin A 
A benzoquinone antineoplastic antibiotic isolated from the bacterium Streptomyces hygroscopicus. Herbimycin binds to and inhibits the cytosolic… 
National Institutes of Health

Related topics

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8 relations

Broader (4)

Anti-Bacterial AgentsAntibiotics, AntineoplasticEnzyme InhibitorsRifabutin
HSP90 Heat-Shock ProteinsNCIt Antineoplastic Agent TerminologySignal Transduction Inhibitionanalogs & derivatives

Papers overview

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Review
2009
Review
2009
Transcription factor profiling unveils the oncogenes involved in the pathogenesis of cutaneous T cell lymphomas
The finding in colon carcinoma that cancerogenesis is a sequence of activation of different oncogenes and inactivation of tumor… 
2006
2006
Integrin signal transduction
![][1] Proteins with phophorylated tyrosines (left) match the location of focal adhesions (right). BURRIDGE A cell resting on… 
2006
2006
Chemical Characteristics and Biological Activities of Herbimycin A and Dihydroherbimycin A Produced by a Soil Isolate Streptomyces sp. AO-0511
A streptomycete strain was isolated from the soil samples from Korea. The chemotaxonomy and 16S rDNA sequencing confirmed that… 
2005
2005
Met 5-enkephalin-induced cardioprotection occurs via transactivation of EGFR and activation of PI 3 K
Cao, Zhiping, Lijuan Liu, and Donna M. Van Winkle. Metenkephalin-induced cardioprotection occurs via transactivation of EGFR and… 
2001
2001
Protein Kinase C and Protein Tyrosine Kinase Activity Contribute to Mitogenic Signaling by Endothelin-1
Endothelin (ET) peptides are potent growth factors that bind to G protein-coupled receptors. Although short-term signals… 
1999
1999
Hydrogen peroxide stimulates tyrosine phosphorylation of focal adhesion kinase in vascular endothelial cells
SURYANARAYANA VEPA,1 WILLIAM M. SCRIBNER,2 NARASIMHAM L. PARINANDI,1 DENIS ENGLISH,3, JOE G. N. GARCIA,1 AND VISWANATHAN… 
1998
1998
Exposure of ligand-binding sites on platelet integrin α IIB / β 3 by phosphorylation of the β 3 subunit
The exposure of ligand-binding sites for adhesive proteins on platelet integrin α IIB }β $ (glycoprotein IIB}IIIA) by… 
1998
1998
Rho A regulates sustained smooth muscle contraction through cytoskeletal reorganization of HSP27.
The ras-related protein Rho p21 regulates various actin-dependent functions, including smooth muscle contraction. However, the… 
1993
1993
Regulation of IgD-receptor expression on murine T cells. II. Upregulation of IgD receptors is obtained after activation of various intracellular second-messenger systems; tyrosine kinase activity is…
The presence of IgD receptors (IgD-R) on T cells during a primary response to antigen causes augmented antibody production and… 
1980
1980
Herbimycin A: an ansamycin antibiotic; X-ray crystal structure.