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HSP90 Heat-Shock Proteins

Known as: Heat Shock Protein 90, Heat-Shock Proteins 90, HSP90 Heat-Shock Proteins [Chemical/Ingredient] 
A family of structurally related proteins that play a role in cell signalling, protein folding and cellular stress responses. The members of this… 
National Institutes of Health

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Related topics

33 relations
17-(dimethylaminoethylamino)-17-demethoxygeldanamycin17-allylamino-17-demethoxygeldanamycin hydroquinoneAlvespimycin HydrochlorideCellular Stress Response

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Hspca protein, mouseHtpG protein, E coliHtpG protein, bacteriaheat-shock protein 98

Papers overview

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Highly Cited
2011
Highly Cited
2011
Heat Shock Protein 90 Inhibitor Is Synergistic with JAK2 Inhibitor and Overcomes Resistance to JAK2-TKI in Human Myeloproliferative Neoplasm Cells
Purpose: We determined the activity of hsp90 inhibitor, and/or Janus-activated kinase 2 (JAK2) tyrosine kinase inhibitor (TKI… 
Highly Cited
2006
Highly Cited
2006
MUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-Src and the molecular chaperone HSP90
The MUC1 heterodimeric transmembrane glycoprotein is aberrantly overexpressed by most human carcinomas. The MUC1 C-terminal… 
Highly Cited
2000
Highly Cited
2000
Crystal Structure and Activity of Human p23, a Heat Shock Protein 90 Co-chaperone*
p23 is a co-chaperone for the heat shock protein, hsp90. This protein binds hsp90 and participates in the folding of a number of… 
Highly Cited
1998
Highly Cited
1998
Differential expression of heat shock proteins in normal and failing human hearts.
BACKGROUND Heat shock proteins (hsp) constitute an endogenous stress response that protects cells from injury. Most work on these… 
Highly Cited
1998
Highly Cited
1998
Prognostic significance of heat shock proteins HSP70 and HSP90 in endometrial carcinomas.
Heat shock proteins HSP70 and HSP90 are sex steroid receptor-associated proteins, and HSP90 expression has reportedly been… 
Highly Cited
1998
Highly Cited
1998
Monoclonal antibodies to mammalian heat shock proteins impair mouse embryo development in vitro.
Two-cell mouse embryos (B6D2F1) were cultured in the presence or absence of 100 microg/ml monoclonal antibodies specific for the… 
Highly Cited
1995
Highly Cited
1995
Analysis of heat‐shock protein expression in myeloid leukaemia cells by flow cytometry
Expression of heat‐shock proteins (hsp) was analysed in the leukaemic cells of 12 patients with acute myeloid leukaemia (AML) and… 
Review
1994
Review
1994
Regulation of protein activities by fusion to steroid binding domains.
Highly Cited
1994
Highly Cited
1994
Characterization of the protein-protein interactions determining the heat shock protein (hsp90.hsp70.hsp56) heterocomplex.
We have reported previously that the three heat shock proteins hsp56, hsp70, and hsp90 exist together in a heterocomplex in human… 
Highly Cited
1989
Highly Cited
1989
Nucleotide sequence and regulation of a human 90-kDa heat shock protein gene.
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