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HSP90 Heat-Shock Proteins

Known as: Heat Shock Protein 90, Heat-Shock Proteins 90, HSP90 Heat-Shock Proteins [Chemical/Ingredient] 
A family of structurally related proteins that play a role in cell signalling, protein folding and cellular stress responses. The members of this… 
National Institutes of Health

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Related topics

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17-(dimethylaminoethylamino)-17-demethoxygeldanamycin17-allylamino-17-demethoxygeldanamycin hydroquinoneAlvespimycin HydrochlorideCellular Stress Response

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Hspca protein, mouseHtpG protein, E coliHtpG protein, bacteriaheat-shock protein 98

Papers overview

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Review
2016
Review
2016
The Role of Heat Shock Proteins in Leukemia.
Heat shock proteins (HSPs) HSP27, HSP70 and HSP90 are molecular chaperones; their expression is increased after exposure of cells… 
2015
2015
Translational Research in Acute Lung Injury and Pulmonary Fibrosis Histone deacetylase inhibitors prevent pulmonary endothelial hyperpermeability and acute lung injury by regulating heat shock…
Joshi AD, Barabutis N, Birmpas C, Dimitropoulou C, Thangjam G, Cherian-Shaw M, Dennison J, Catravas JD. Histone deacetylase… 
2013
2013
Experimentally Guided Structural Modeling and Dynamics Analysis of Hsp90-p53 Interactions: Allosteric Regulation of the Hsp90 Chaperone by a Client Protein
A fundamental role of the Hsp90 chaperone system in mediating maturation of protein clients is essential for the integrity of… 
2010
2010
DcHsp17.7, a Small Heat Shock Protein from Carrot, Is Upregulated under Cold Stress and Enhances Cold Tolerance by Functioning as a Molecular Chaperone
The expression profile and functional properties of DcHsp17.7, a small heat shock protein from carrot (Daucus carota L.), were… 
Highly Cited
2008
Highly Cited
2008
Enhanced methyltransferase activity of SMYD3 by the cleavage of its N-terminal region in human cancer cells
Histone methylation is involved in the regulation of gene expression and DNA replication through alteration of chromatin… 
2008
2008
A Phase 1 dose-escalation study of the safety and pharmacokinetics (PK) of the oral Hsp90 inhibitor SNX-5422
14613 Background: SNX-5422 is an oral pro-drug of SNX-2112, a potent and highly selective small-molecule inhibitor of the… 
2002
2002
Regulation of Hsp 90 ATPase Activity by the Co-chaperone Cdc 37 p / p 50 cdc 37
From the ‡Pharmaceutical Optical Spectroscopy Centre, Department of Pharmacy, the §Division of Life Sciences, King’s College… 
2000
2000
p53-independent association between SV40 large T antigen and the major cytosolic heat shock protein, HSP90
The simian double strand DNA tumor virus SV40 encodes the 90-kDa multi-functional protein, large T antigen (LT). LT functions by… 
2000
2000
Hsp 90 Regulates p 50 cdc 37 Function during the Biogenesis of the Active Conformation of the Heme-regulated eIF 2 a Kinase *
Recent studies indicate that p50 facilitates Hsp90mediated biogenesis of certain protein kinases. In this report, we examined… 
1998
1998
Intestinal Expression of Human Heat Shock Protein 90 in Patients with Crohn's Disease and Ulcerative Colitis
Heat shock proteins are induced by severalstress factors and are potential antigens in autoimmunedisorders. Expression of heat… 
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