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granzyme B

Known as: Cytotoxic T-Lymphocyte Associated 1 Protein, Granzyme Like Protein III, Cytotoxic Serine Protease B 
National Institutes of Health

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Related topics

5 relations
GZMB geneGZMB wt AlleleGranzyme B Ag:PrThr:Pt:Tiss:Ord:Immune stain

Narrower (1)

GZMB protein, human

Broader (1)

Granzymes

Papers overview

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2017
2017
Protease-activated receptor-1 activation by granzyme B causes neurotoxicity that is augmented by interleukin-1β
The cause of neurodegeneration in progressive forms of multiple sclerosis is unknown. We investigated the impact of specific… 
2011
2011
hSMG-1 is a granzyme B-associated stress-responsive protein kinase
Granzyme B plays a key role in cell-mediated programmed cell death. We previously demonstrated that p53 is a functional… 
Highly Cited
2008
Highly Cited
2008
Granzyme B delivery via perforin is restricted by size, but not by heparan sulfate-dependent endocytosis
How granzymes gain entry into the cytosol of target cells during killer cell attack has been the subject of several studies in… 
2002
2002
The human homologue of the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis.
In the present study, we demonstrate that a human homologue of Ufd2p (a yeast protein that catalyses the formation of long… 
1996
1996
Binding of Granzyme B in the Nucleus of Target Cells
Granzyme B (cytotoxic cell proteinase 1) is a serine proteinase that has been implicated in cytotoxic T lymphocyte-induced… 
1995
1995
The peptide loop consisting of amino acids 139-157 of human granzyme B (fragmentin 2) contains an immunodominant epitope recognized by the mouse.
Highly Cited
1995
Highly Cited
1995
Rescue from granzyme B-induced apoptosis by Wee1 kinase
Granzymes are a family of granule-associated serine esterases that mediate apoptosis by cytotoxic T lymphocytes and natural… 
Highly Cited
1994
Highly Cited
1994
Conversion of the substrate specificity of mouse proteinase granzyme B
Mouse granzyme B is the prototypic member of a subfamily of serine proteinases expressed in cytolytic lymphocytes. Molecular… 
Highly Cited
1993
Highly Cited
1993
Immunopurification of functional Asp-ase (natural killer cell granzyme B) using a monoclonal antibody.
Enzymatically active granule-associated serine protease ("granzyme") B has been purified from human NK cell lysates, using novel… 
1990
1990
Structural organization of the hCTLA-1 gene encoding human granzyme B.
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