glycosaminoglycan biosynthetic process

Known as: glycosaminoglycan biosynthesis, glycosaminoglycan anabolism, glycosaminoglycan formation 
The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars… (More)
National Institutes of Health

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Highly Cited
2017
Highly Cited
2017
Rare and low-frequency coding variants alter human adult height
Height is a highly heritable, classic polygenic trait with approximately 700 common associated variants identified through genome… (More)
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Highly Cited
2011
Highly Cited
2011
Hypoxia mediated isolation and expansion enhances the chondrogenic capacity of bone marrow mesenchymal stromal cells
The capacity of bone marrow mesenchymal stromal cells (BMSCs) to be induced into chondrocytes has drawn much attention for cell… (More)
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Highly Cited
2009
Highly Cited
2009
Enhanced in vitro chondrogenesis of primary mesenchymal stem cells by combined gene transfer.
Because articular cartilage has a poor regeneration capacity, numerous cell-based approaches to therapy are currently being… (More)
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Highly Cited
2006
Highly Cited
2006
Genistein-mediated inhibition of glycosaminoglycan synthesis as a basis for gene expression-targeted isoflavone therapy for mucopolysaccharidoses
Mucopolysaccharidoses (MPS) are inherited, severe, progressive, metabolic disorders caused by deficiencies in different enzymes… (More)
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Highly Cited
2005
Highly Cited
2005
Influence of oxygen on the proliferation and metabolism of adipose derived adult stem cells.
Articular cartilage is an avascular connective tissue that exhibits little intrinsic capacity for repair. Articular cartilage… (More)
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Review
2003
Review
2003
Sulfotransferases in glycosaminoglycan biosynthesis.
Most of the sulfotransferases participating in glycosaminoglycan biosynthesis have now been identified. Their essential role in… (More)
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Highly Cited
2001
Highly Cited
2001
YKL-40 (cartilage gp-39) induces proliferative events in cultured chondrocytes and synoviocytes and increases glycosaminoglycan synthesis in chondrocytes.
YKL-40 (cartilage gp-39), is a mammalian glycoprotein related in sequence to chitinases. Its function is unknown, but it is… (More)
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Highly Cited
2001
Highly Cited
2001
Interleukin-1beta down-regulates the expression of glucuronosyltransferase I, a key enzyme priming glycosaminoglycan biosynthesis: influence of glucosamine on interleukin-1beta-mediated effects in…
OBJECTIVE To assess the variations of galactose-beta-1,3-glucuronosyltransferase I (GlcAT-I) expression related to the decrease… (More)
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Highly Cited
1989
Highly Cited
1989
Some biochemical and biophysical parameters for the study of the pathogenesis of osteoarthritis: a comparison between the processes of ageing and degeneration in human hip cartilage.
We have investigated the changes in some of the biochemical and biophysical properties of human femoral head cartilage on the one… (More)
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Highly Cited
1982
Highly Cited
1982
Lumen formation by epithelial cell lines in response to collagen overlay: a morphogenetic model in culture.
Two cell lines--Madin-Darby canine kidney (MDCK) and normal murine mammary gland (NMuMG)--growing as monolayers on collagen gels… (More)
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