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The fine structure of the cribriform meshwork in normal and glaucomatous eyes as seen in tangential sections.
Electron microscopic serial sections in a tangential plane through the inner wall of Schlemm's canal and the trabecular meshwork in normal and glaucomatous eyes revealed a characteristic network of
Ultrahistochemical studies on tangential sections of the trabecular meshwork in normal and glaucomatous eyes.
The composition of the extracellular material of the cribriform meshwork was compared in five normal and 13 glaucomatous eyes of the same age group and the fibrillar components, which partly could be studied only after enzymatic treatment, showed qualitative differences between normal and glaucolysis eyes.
Scanning electron microscopic studies of the zonular apparatus in human and monkey eyes.
  • J. Rohen
  • Chemistry, Medicine
    Investigative ophthalmology & visual science
  • 1 February 1979
Two functionally different sets of zonular fibers are revealed: the "main fiber" and the "tension fiber" system, which are connected, forming a broad, sagittally oriented "zonular plexus" within the pars plicata of the ciliary body.
Why is intraocular pressure elevated in chronic simple glaucoma? Anatomical considerations.
  • J. Rohen
  • Medicine
  • 1 July 1983
Ultrastructural analysis of 400 trabeculectomy specimens of glaucomatous eye revealed three types of extracellular deposits within the cribriform layer of the trabecular meshwork. One of these
Quantitative analysis of 'plaque material' in the inner- and outer wall of Schlemm's canal in normal- and glaucomatous eyes.
The findings indicate that in addition to the age-related increase in plaque material, there is in glaucomatous eyes some plaque material which is distributed unevenly in the inner- and outer-wall of Schlemm's canal, indicating that elevated intraocular pressure alone can not be responsible for plaque formation.
Morphology of the trabecular meshwork and inner-wall endothelium after cationized ferritin perfusion in the monkey eye.
There are paracellular routes through the inner-wall endothelium by which high molecular-weight substances such as ferritin and macrophages can leave the anterior chamber, demonstrating that there are both transcytoplasmic andParacellular mechanisms of aqueous outflow that may vary under different conditions of pressure or flow.
Age-related changes of the human ciliary muscle. A quantitative morphometric study
There might be a functional relationship between the observed age-changes in the ciliary muscle system and the phenomenon of the so-called 'lens paradox' (steepening of the anterior and posterior curvatures of the disaccommodated lens with age).
Ultrastructure of the trabecular meshwork in untreated cases of primary open-angle glaucoma (POAG).
Patients suffering from primary open-angle glaucoma who had received no, or only minor, medication prior to surgery were ultrastructurally and quantitatively analysed and revealed thickened trabeculae, increased amounts of plaque-material deposited within the cribriform layer and an abundance of long spacing collagen.
Quantitative analysis of 'plaque material' between ciliary muscle tips in normal- and glaucomatous eyes.
The quantitative evaluation of all three types of ciliary muscle (c.m.) plaques showed that in normal eyes the amount of c.m. plaques increases with age and correlates with the amounts of plaques in the inner wall of Schlemm's canal, and in cases of chronic simple glaucoma the amounts did not significantly correlate with age.
Age-related changes of the ciliary muscle in comparison with changes induced by treatment with prostaglandin F2α. An ultrastructural study in rhesus and cynomolgus monkeys
Lack of attachment between basal lamina and altered muscle cells in aged eyes might indicate an involvement of the extracellular matrix in age-related changes of the individual ciliary muscle cells.