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glaucine

Known as: 5,6,6a,7-tetrahydro-1,2,9,10-tetramethoxy-6- methyl-4H-dibenzo(de,g)quinoline 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (4)

AntioxidantsAntitussive AgentsAporphinesParasympatholytics

Narrower (3)

glaucine phosphateglaucine, (R)-isomertussiglaucin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Digitonin synergistically enhances the cytotoxicity of plant secondary metabolites in cancer cells.
In phytotherapy, extracts from medicinal plants are employed which contain mixtures of secondary metabolites. Their modes of… Expand
2007
2007
Detection of the pharmaceutical agent glaucine as a recreational drug
Keywords Glaucine.Recreationaldrugs.Druglegislation.ToxicologicalscreeningWe would like to report a case of toxicity related… Expand
2005
2005
Structure-affinity relationships of halogenated predicentrine and glaucine derivatives at D1 and D2 dopaminergic receptors: halogenation and D1 receptor selectivity.
Halogenation of the aporphine alkaloid boldine at the 3-position leads to increased affinity for rat brain D(1)-like dopaminergic… Expand
2000
2000
Effects of inhaled glaucine on pulmonary responses to antigen in sensitized guinea pigs.
The alkaloid (S)-(+)-1,2,9,10-tetramethoxyaporphine (glaucine) is a phosphodiesterase 4 inhibitor with bronchodilator and anti… Expand
Highly Cited
1999
Highly Cited
1999
Bronchodilator and anti‐inflammatory activities of glaucine: In vitro studies in human airway smooth muscle and polymorphonuclear leukocytes
Selective phosphodiesterase 4 (PDE4) inhibitors are of potential interest in the treatment of asthma. We examined the effects of… Expand
1999
1999
Biochemical and Behavioral Effects of Boldine and Glaucine on Dopamine Systems
The aporphine alkaloids boldine and glaucine have been reported to show "neuroleptic-like" actions in mice, suggesting that they… Expand
Highly Cited
1995
Highly Cited
1995
The inhibitory effects of boldine, glaucine, and probucol on TPA-induced down regulation of gap junction function. Relationships to intracellular peroxides, protein kinase C translocation, and…
The naturally occurring antioxidant boldine and its di-methoxy analogue glucine, as well as the drug antioxidant probucol, all… Expand
1992
1992
Multiple actions of glaucine on cyclic nucleotide phosphodiesterases, α1‐adrenoceptor and benzothiazepine binding site at the calcium channel
1 In the present study, the properties of glaucine (an aporphine structurally related to papaverine) were compared with those of… Expand
1988
1988
Neuroleptic-like, anticonvulsant and antinociceptive effects of aporphine alkaloids: bulbocapnine, corytuberine, boldine and glaucine.
  • G. Zetler
  • Archives internationales de pharmacodynamie et de…
  • 1988
    • Corpus ID: 31700487
The aporphine alkaloids bulbocapnine, corytuberine, boldine and glaucine were studied in mice and compared with haloperidol… Expand
1984
1984
Efficacy and tolerability of glaucine as an antitussive agent.
One hundred and thirty out-patients, affected by acute and chronic cough caused by upper respiratory tract inflammation, took… Expand
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