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Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb.
- A. Izzo, F. Borrelli, R. Capasso, V. Di Marzo, R. Mechoulam
- Trends in pharmacological sciences
- 1 October 2009
Delta(9)-tetrahydrocannabinol binds cannabinoid (CB(1) and CB(2)) receptors, which are activated by endogenous compounds (endocannabinoids) and are involved in a wide range of physiopathological… Expand
Bacopa monniera, a reputed nootropic plant: an overview.
Bacopa monniera (BM), a traditional Ayurvedic medicine, used for centuries as a memory enhancing, anti-inflammatory, analgesic, antipyretic, sedative and antiepileptic agent. The plant, plant extract… Expand
The plant kingdom as a source of anti‐ulcer remedies
Phytogenic agents have traditionally been used by herbalists and indigenous healers for the prevention and treatment of peptic ulcer. This article reviews the anti‐acid/anti‐peptic, gastro‐protective… Expand
Herb–Drug Interactions with St John’s Wort (Hypericum perforatum): an Update on Clinical Observations
St John’s wort (SJW) extracts, prepared from the aerial parts of Hypericum perforatum, contain numerous pharmacologically active ingredients, including naphthodianthrones (e.g., hypericin and its… Expand
Phytochemical compounds involved in the anti-inflammatory effect of propolis extract.
Two ethanolic propolis extracts (EPE) with and without the caffeic acid phenethyl ester (CAPE), CAPE and galangin (major components of propolis) were investigated for anti-inflammatory activity in… Expand
Fatty acid amide hydrolase controls mouse intestinal motility in vivo.
BACKGROUND & AIMS Fatty acid amide hydrolase (FAAH) catalyzes the hydrolysis both of the endocannabinoids (which are known to inhibit intestinal motility) and other bioactive amides… Expand
Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer
- G. Aviello, B. Romano, +5 authors A. Izzo
- Medicine, Chemistry
- Journal of Molecular Medicine
- 10 January 2012
Colon cancer affects millions of individuals in Western countries. Cannabidiol, a safe and non-psychotropic ingredient of Cannabis sativa, exerts pharmacological actions (antioxidant and intestinal… Expand
Green tea (Camellia sinensis) for the prevention of cancer.
- K. Boehm, F. Borrelli, +4 authors M. Horneber
- The Cochrane database of systematic reviews
- 8 July 2009
BACKGROUND Tea is one of the most commonly consumed beverages worldwide. Teas from the plant Camellia sinensis can be grouped into green, black and oolong tea. Cross-culturally tea drinking habits… Expand
An endogenous cannabinoid tone attenuates cholera toxin-induced fluid accumulation in mice.
BACKGROUND & AIMS Cholera toxin (CT) is the most recognizable enterotoxin causing secretory diarrhea, a major cause of infant morbidity and mortality throughout the world. In this study, we… Expand
Free radical scavenging capacity and protective effect of Bacopa monniera L. on DNA damage
- A. Russo, A. Izzo, F. Borrelli, M. Renis, A. Vanella
- Chemistry, Medicine
- Phytotherapy research : PTR
- 1 September 2003
Bacopa monniera L. (family Scrophulariaceae) (BM) is an Ayurvedic medicine, clinically used for memory enhancing, epilepsy, insomnia and as a mild sedative. In this work, the free radical scavenging… Expand