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Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb.
- A. Izzo, F. Borrelli, R. Capasso, V. Di Marzo, R. Mechoulam
- Trends in pharmacological sciences
- 1 October 2009
Cannabidiol and Delta(9)-tetrahydrocannabivarin, a novel CB(1) antagonist which exerts potentially useful actions in the treatment of epilepsy and obesity are given special emphasis. Expand
Bacopa monniera, a reputed nootropic plant: an overview.
Investigation must be continued in the recently observed actions of Bacopa monniera to evidence any side effects and possible interactions between this herbal medicine and synthetic drugs. Expand
The plant kingdom as a source of anti‐ulcer remedies
Despite progress in conventional chemistry and pharmacology in producing effective drugs, the plant kingdom might provide a useful source of new anti‐ulcer compounds for development as pharmaceutical entities or as simple dietary adjuncts to existing therapies. Expand
Herb–Drug Interactions with St John’s Wort (Hypericum perforatum): an Update on Clinical Observations
St John’s wort extracts, prepared from the aerial parts of Hypericum perforatum, contain numerous pharmacologically active ingredients, including naphthodianthrones, which are widely used for the treatment of mild-to-moderate depression. Expand
Phytochemical compounds involved in the anti-inflammatory effect of propolis extract.
Results suggest that the anti-inflammatory activity of propolis is due to CAPE, and EPE without CAPE and galangin did not exhibit anti- inflammation effects in acute and chronic inflammation. Expand
Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer
- G. Aviello, B. Romano, +5 authors A. Izzo
- Chemistry, Medicine
- Journal of Molecular Medicine
- 10 January 2012
It is concluded that cannabidiol exerts chemopreventive effect in vivo and reduces cell proliferation through multiple mechanisms in colorectal carcinoma cell lines. Expand
Green tea (Camellia sinensis) for the prevention of cancer.
- K. Boehm, F. Borrelli, +4 authors M. Horneber
- The Cochrane database of systematic reviews
- 8 July 2009
There is insufficient and conflicting evidence to give any firm recommendations regarding green tea consumption for cancer prevention, and drinking green tea appears to be safe at moderate, regular and habitual use. Expand
Free radical scavenging capacity and protective effect of Bacopa monniera L. on DNA damage
- A. Russo, A. Izzo, F. Borrelli, M. Renis, A. Vanella
- Chemistry, Medicine
- Phytotherapy research : PTR
- 1 September 2003
Experimental evidence suggests that because of its antioxidant activity, this Ayurvedic drug may be useful in the treatment of human pathologies in which free radical production plays a key role. Expand
Fatty acid amide hydrolase controls mouse intestinal motility in vivo.
It is concluded that FAAH is a physiologic regulator ofestinal motility and a potential target for the development of drugs capable of reducing intestinal motility. Expand
Pharmacological effects of Cimicifuga racemosa.
The results suggest that C. racemosa possesses a central activity instead of a hormonal effect, and further biological and chemical investigations are required to define its mechanism of action and to identify the compounds responsible of its actions. Expand