gemifloxacin

Known as: 7-(3-aminomethyl-4-methoxyimino-pyrrolidine-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-(1,8)-naphthyridine-3-carboxylic acid, gemifloxacin [Chemical/Ingredient] 
A fluoroquinolone antibiotic with antimicrobial property. Gemifloxacin enters bacterial cells by diffusion through integral membrane porin pathway… (More)
National Institutes of Health

Papers overview

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2014
2014
BACKGROUND Ceftriaxone is the foundation of currently recommended gonorrhea treatment. There is an urgent need for backup… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVES The Alexander Project is a continuing surveillance study, begun in 1992, examining the susceptibility of pathogens… (More)
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2002
2002
BACKGROUND Gemifloxacin is an enhanced-affinity quinolone with potent activity against lower respiratory tract pathogens… (More)
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Review
2002
Review
2002
Streptococcus pneumoniae is an important pathogen in many community-acquired respiratory infections in the United States and a… (More)
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2002
2002
Gemifloxacin is a recently developed fluoroquinolone with potent activity against Streptococcus pneumoniae. We show that the drug… (More)
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2002
2002
A clinical isolate of Streptococcus pneumoniae was transformed with a plasmid containing the lux operon of Photorhabdus… (More)
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Highly Cited
2001
Highly Cited
2001
A total of 1,531 recent clinical isolates of Streptococcus pneumoniae were collected from 33 medical centers nationwide during… (More)
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2000
2000
The activities of gemifloxacin compared to those of nine other agents was tested against a range of penicillin-susceptible and… (More)
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2000
2000
In vitro activities of seven fluoroquinolones against 140 clinical Acinetobacter baumannii isolates representing 138 different… (More)
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Review
2000
Review
2000
The history of the development of the quinolones is described from the first quinolone, nalidixic acid, via the first 6… (More)
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