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SB-265805

Known as: SB 265805 
National Institutes of Health

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1 relation

Broader (1)

gemifloxacin

Papers overview

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2001
2001
In Vitro Activity of Gemifloxacin (SB-265805, LB20304a) against Legionella pneumophila and Its Pharmacokinetics in Guinea Pigs with L. pneumophila Pneumonia
ABSTRACT The activity of gemifloxacin against intracellularLegionella pneumophila and for the treatment of guinea pigs with L… 
2001
2001
Comparative in vitro activity of the new quinolone gemifloxacin (SB-265805) with other fluoroquinolones against respiratory tract pathogens.
The in vitro activity of gemifloxacin (SB-265805) was compared with that of other fluoroquinolones against 302 clinical isolates… 
Highly Cited
2000
Highly Cited
2000
Pharmacokinetics and Tolerability of Gemifloxacin (SB-265805) after Administration of Single Oral Doses to Healthy Volunteers
ABSTRACT Gemifloxacin (known as SB-265805 or LB-20304) is a potent, novel fluoroquinolone compound with a broad spectrum of… 
2000
2000
In vitro activity of gemifloxacin (SB-265805) compared with 14 other antimicrobials against intestinal pathogens.
We studied the in vitro activity of gemifloxacin (SB-265805) and 14 comparator antimicrobials against 288 recent isolates of… 
Highly Cited
2000
Highly Cited
2000
In Vitro Activities of Six Fluoroquinolones against 250 Clinical Isolates of Mycobacterium tuberculosisSusceptible or Resistant to First-Line Antituberculosis Drugs
ABSTRACT Two hundred fifty isolates of Mycobacterium tuberculosis were evaluated for susceptibility to ciprofloxacin, ofloxacin… 
2000
2000
The bactericidal activity of gemifloxacin (SB-265805).
The bactericidal activity and mechanisms of action of the new fluoroquinolone gemifloxacin were investigated against the… 
Highly Cited
2000
Highly Cited
2000
Comparative in vitro activity and post-antibiotic effect of gemifloxacin against Legionella spp.
The comparative in vitro potency and post-antibiotic effect (PAE) of gemifloxacin (SB-265805), moxifloxacin, trovafloxacin… 
Highly Cited
2000
Highly Cited
2000
Comparative potency of gemifloxacin, new quinolones, macrolides, tetracycline and clindamycin against Mycoplasma spp.
This study determined the comparative in vitro potency of the new investigative quinolone gemifloxacin (SB-265805) using low… 
2000
2000
Purification of pneumococcal type II topoisomerases and inhibition by gemifloxacin and other quinolones.
Topoisomerase IV and DNA gyrase were purified from a ciprofloxacin-sensitive Streptococcus pneumoniae strain and from two… 
Highly Cited
1999
Highly Cited
1999
Anti-streptococcal activity of SB-265805 (LB20304), a novel fluoronaphthyridone, compared with five other compounds, including quality control guidelines.
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