Naphthyridines

Known as: Naphthyridines [Chemical/Ingredient] 
 
National Institutes of Health

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1,5-naphthyridinone oxabicyclooctane1-methoxy-canthin-6-one2,7-diamido-1,8-naphthyridine2,7-diamino-1,8-naphthyridine
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naphthyridine

Papers overview

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2017
2017
Preparation of Polyfunctional Naphthyridines by Cobalt-Catalyzed Cross-Couplings of Halogenated Naphthyridines with Magnesium and Zinc Organometallics
CoCl2 (5%) catalyzes cross-couplings of various halogenated naphthyridines with alkyl- and arylmagnesium halides. Also, arylzinc… (More)
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2014
2014
Naphthyridines as novel BET family bromodomain inhibitors.
Bromodomains (BRDs) are small protein domains found in a variety of proteins that recognize and bind to acetylated histone tails… (More)
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2012
2012
A new 4-phenyl-1,8-naphthyridine derivative affects carcinoma cell proliferation by impairing cell cycle progression and inducing apoptosis.
In targeted cancer therapy the search for novel molecules led to the discovery of a plethora of small organic molecules… (More)
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2010
2010
QSAR study of substituted 1,3,4-oxadiazole naphthyridines as HIV-1 integrase inhibitors.
A linear quantitative structure activity relationship (QSAR) model is presented for modeling and predicting the inhibition of HIV… (More)
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2009
2009
1,3,4-Oxadiazole substituted naphthyridines as HIV-1 integrase inhibitors. Part 2: SAR of the C5 position.
The use of a 1,3,4-oxadiazole in combination with an 8-hydroxy-1,6-naphthyridine ring system has been shown to deliver potent… (More)
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2009
2009
The use of oxadiazole and triazole substituted naphthyridines as HIV-1 integrase inhibitors. Part 1: Establishing the pharmacophore.
A series of HIV-1 integrase inhibitors containing a novel metal binding motif consisting of the 8-hydroxy-1,6-naphthyridine core… (More)
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2007
2007
Novel naphthyridines are histamine H3 antagonists and serotonin reuptake transporter inhibitors.
A series of novel tetrahydronaphthyridine-based histamine H(3) ligands that have serotonin reuptake transporter inhibitor… (More)
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2005
2005
Simple and Efficient Synthesis of 2,7-Difunctionalized-1,8- Naphthyridines
The syntheses in good yields of some new difunctionalized 1,8-naphthyridines 4, 6, 8 and 9 and a novel triethylene glycol ether… (More)
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2005
2005
Synthesis, characterization and antimicrobial activities of fused 1,6-naphthyridines
In recent years, naphthyridines with fused rings like dibenzo, benzopyrido, diazanaphtho and benzoquinolino have been widely… (More)
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1993
1993
Quinolone antibacterial agents: relationship between structure and in vitro inhibition of the human cytochrome P450 isoform CYP1A2.
The inhibitory effect of 44 quinolone antibacterials and derivatives (common structure, 4-oxoquinoline-3-carboxylic acid) on… (More)
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