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Naphthyridines

Known as: Naphthyridines [Chemical/Ingredient] 
National Institutes of Health

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1,5-naphthyridinone oxabicyclooctane1-methoxy-canthin-6-one2,7-diamido-1,8-naphthyridine2,7-diamino-1,8-naphthyridine
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In Bloodagonistsantagonists & inhibitorschemical synthesis

Broader (1)

naphthyridine

Papers overview

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Highly Cited
2013
Highly Cited
2013
On water: silver-catalyzed domino approach for the synthesis of benzoxazine/oxazine-fused isoquinolines and naphthyridines from o-alkynyl aldehydes.
An operationally simple domino approach for the silver-catalyzed synthesis of oxazine/benzoxazine-fused isoquinolines 5a-q and… Expand
2010
2010
QSAR study of substituted 1,3,4-oxadiazole naphthyridines as HIV-1 integrase inhibitors.
A linear quantitative structure activity relationship (QSAR) model is presented for modeling and predicting the inhibition of HIV… Expand
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Highly Cited
2009
Highly Cited
2009
The use of oxadiazole and triazole substituted naphthyridines as HIV-1 integrase inhibitors. Part 1: Establishing the pharmacophore.
A series of HIV-1 integrase inhibitors containing a novel metal binding motif consisting of the 8-hydroxy-1,6-naphthyridine core… Expand
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Highly Cited
2009
Highly Cited
2009
1,3,4-Oxadiazole substituted naphthyridines as HIV-1 integrase inhibitors. Part 2: SAR of the C5 position.
The use of a 1,3,4-oxadiazole in combination with an 8-hydroxy-1,6-naphthyridine ring system has been shown to deliver potent… Expand
Review
2007
Review
2007
Synthesis and structure-activity relationships of potent antitumor active quinoline and naphthyridine derivatives.
The disease of cancer has been ranked second after cardiovascular diseases and plant-derived molecules have played an important… Expand
Review
2003
Review
2003
Discovery and SAR of novel Naphthyridines as potent inhibitors of spleen tyrosine kinase (SYK).
The discovery of novel 5,7-disubstituted[1,6]naphthyridines as potent inhibitors of Spleen Tyrosine Kinase (SYK) is discussed… Expand
Highly Cited
2002
Highly Cited
2002
Synthesis of substituted isoquinolines by electrophilic cyclization of iminoalkynes.
The tert-butylimines of o-(1-alkynyl)benzaldehydes and analogous pyridinecarbaldehydes have been cyclized under very mild… Expand
Highly Cited
2001
Highly Cited
2001
Synthesis of isoquinolines and naphthyridines by electrophilic ring closure of iminoalkynes.
Substituted isoquinolines and naphthyridines have been prepared in good to excellent yields by the reaction of iminoalkynes with… Expand
Highly Cited
2001
Highly Cited
2001
Complexation-induced unfolding of heterocyclic ureas. Simple foldamers equilibrate with multiply hydrogen-bonded sheetlike structures.
The synthesis and conformational studies of heterocyclic ureas (amides) 1-7 and their concentration-dependent unfolding to form… Expand
Highly Cited
1980
Highly Cited
1980
Heterocyclic analogues of the antihypertensive beta-adrenergic blocking agent (S)-2-[3-(ter-butylamino)-2-hydroxypropoxy]-3-cyanopyridine.
The synthesis of a series of isoelectronic analogues of (S)-2-[3-(tert-butylamino)-2-hydroxypropoxy]-3-cyanopyridine (1) are… Expand
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