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Naphthyridines

Known as: Naphthyridines [Chemical/Ingredient] 
National Institutes of Health

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1,5-naphthyridinone oxabicyclooctane1-methoxy-canthin-6-one2,7-diamido-1,8-naphthyridine2,7-diamino-1,8-naphthyridine
In Bloodagonistsantagonists & inhibitorschemical synthesis

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naphthyridine

Papers overview

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2014
2014
Naphthyridines as Novel BET Family Bromodomain Inhibitors
Bromodomains (BRDs) are small protein domains found in a variety of proteins that recognize and bind to acetylated histone tails… 
Highly Cited
2013
Highly Cited
2013
On water: silver-catalyzed domino approach for the synthesis of benzoxazine/oxazine-fused isoquinolines and naphthyridines from o-alkynyl aldehydes.
An operationally simple domino approach for the silver-catalyzed synthesis of oxazine/benzoxazine-fused isoquinolines 5a-q and… 
Highly Cited
2013
Highly Cited
2013
Silver-catalyzed tandem synthesis of naphthyridines and thienopyridines via three-component reaction.
An efficient approach for the silver-catalyzed regioselective tandem synthesis of highly functionalized 1,2-dihydrobenzo[1,6… 
Highly Cited
2012
Highly Cited
2012
Copper-catalyzed tandem synthesis of indolo-, pyrrolo[2,1-a]isoquinolines, naphthyridines and bisindolo/pyrrolo[2,1-a]isoquinolines via hydroamination of ortho-haloarylalkynes followed by C-2…
An efficient approach for the copper-catalyzed regioselective tandem synthesis of diversely substituted indolo[2,1-a… 
2010
2010
Synthesis of aryl-heteroaryl ureas (AHUs) based on 4-aminoquinoline and their evaluation against the insulin-like growth factor receptor (IGF-1R).
Highly Cited
2009
Highly Cited
2009
The use of oxadiazole and triazole substituted naphthyridines as HIV-1 integrase inhibitors. Part 1: Establishing the pharmacophore.
Review
2007
Review
2007
Synthesis and structure-activity relationships of potent antitumor active quinoline and naphthyridine derivatives.
The disease of cancer has been ranked second after cardiovascular diseases and plant-derived molecules have played an important… 
Highly Cited
2002
Highly Cited
2002
Synthesis of substituted isoquinolines by electrophilic cyclization of iminoalkynes.
The tert-butylimines of o-(1-alkynyl)benzaldehydes and analogous pyridinecarbaldehydes have been cyclized under very mild… 
Highly Cited
2001
Highly Cited
2001
Complexation-induced unfolding of heterocyclic ureas. Simple foldamers equilibrate with multiply hydrogen-bonded sheetlike structures.
The synthesis and conformational studies of heterocyclic ureas (amides) 1-7 and their concentration-dependent unfolding to form… 
Highly Cited
1980
Highly Cited
1980
Heterocyclic analogues of the antihypertensive beta-adrenergic blocking agent (S)-2-[3-(ter-butylamino)-2-hydroxypropoxy]-3-cyanopyridine.
The synthesis of a series of isoelectronic analogues of (S)-2-[3-(tert-butylamino)-2-hydroxypropoxy]-3-cyanopyridine (1) are… 
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