naphthyridine

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1964-2016
05101519642016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Bromodomains (BRDs) are small protein domains found in a variety of proteins that recognize and bind to acetylated histone tails… (More)
Is this relevant?
2010
2010
A novel 2,6-naphthyridine was identified by high throughput screen (HTS) as a dual protein kinase C/D (PKC/PKD) inhibitor. PKD… (More)
Is this relevant?
2010
2010
A linear quantitative structure activity relationship (QSAR) model is presented for modeling and predicting the inhibition of HIV… (More)
Is this relevant?
2009
2009
A novel series of topoisomerase I (Top I) inhibitors were designed on the basis of camptothecin using scaffold modification… (More)
  • figure 1
  • table 1
  • figure 2
  • table 2
  • figure 4
Is this relevant?
2008
2008
To gain further insight into the understanding of the antiviral resistance patterns and mechanisms of the integrase strand… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
The increasing incidence of resistance to current HIV-1 therapy underscores the need to develop antiretroviral agents with new… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
2003
2003
The binding of a dimeric form of the 2-amino-1,8-naphthyridine derivative (naphthyridine dimer) to a human telomeric sequence… (More)
Is this relevant?
2002
2002
In an attempt to search for clinically useful antitumor agents, we have discovered that a series of 1,7-disubstituted-6-fluoro-1… (More)
Is this relevant?
2001
2001
Dimeric 2-amino-1,8-naphthyridine selectively binds to a G-G mismatch with high affinity (K(d) = 53 nM). We have investigated a… (More)
Is this relevant?
1988
1988
A series of 7,8-disubstituted 1-cyclopropyl-6-fluoroquinoline-3-carboxylic acids, 7-substituted 1-cyclopropyl-6-fluoro-1,8… (More)
Is this relevant?