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fosinoprilat

Known as: L-Proline, 4-cyclohexyl-1-((hydroxy(4-phenylbutyl)phosphinyl)acetyl)-, trans-, SQ 27,519, fosinoprilic acid 
A phosphinic acid-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Fosinoprilat specifically and… 
National Institutes of Health

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9 relations

Broader (4)

Angiotensin-Converting Enzyme InhibitorsAnti-Arrhythmia AgentsAntihypertensive AgentsFosinopril
Fosinopril Sodium 10 MG / Hydrochlorothiazide 12.5 MG Oral TabletFosinopril Sodium 20 MG / Hydrochlorothiazide 12.5 MG Oral TabletFosinopril Sodium 20 MG Oral TabletFosinopril Sodium 40 MG Oral Tablet

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Identification of metabolites of fosinopril produced by human and rat liver microsomes with liquid chromatography-mass spectrometry.
2005
2005
Microemulsion liquid chromatographic method for characterisation of fosinopril sodium and fosinoprilat separation with chemometrical support
The properties of the eluent are the essential factors governing the efficiency in the high-performance liquid chromatography… 
2001
2001
Angiotensin converting enzyme inhibition improves cardiac neuronal uptake of noradrenaline in spontaneously hypertensive rats
Objectives It has been shown that a diminished sympathetic activity contributes to the hypotensive and cardioprotective actions… 
2000
2000
Liquid chromatography/electrospray tandem mass spectrometry method for the quantitation of fosinoprilat in human serum using automated 96-well solid-phase extraction for sample preparation.
A sensitive, specific, accurate and reproducible liquid chromatography/electrospray tandem mass spectrometry method was developed… 
1999
1999
Acute NEP/ACE inhibition by omapatrilat is superior to ace inhibition alone in mediating favorable cardiorenal and humoral actions in mild heart failure
1997
1997
Pharmacokinetics of Fosinoprilat in Chinese and Whites After Intravenous Administration
The pharmacokinetics of fosinoprilat was studied in 12 healthy Chinese men after a 7.5 mg intravenous dose of fosinoprilat. The… 
1995
1995
Effects of metalloproteinase inhibitors on leukotriene A4 hydrolase in human airway epithelial cells.
1995
1995
Fosinopril treatment of pregnant rats: developmental toxicity, fetal angiotensin-converting enzyme inhibition, and fetal angiotensin II receptor regulation.
Highly Cited
1992
Highly Cited
1992
Inhibition by converting enzyme inhibitors of pig kidney aminopeptidase P.
Several inhibitors of angiotensin converting enzyme were also found to inhibit aminopeptidase P, whereas inhibitors of other… 
1992
1992
Local Potentiation of Bradykinin‐Induced Vasodilation by Converting‐Enzyme Inhibition in Isolated Coronary Arteries
The interaction of angiotensin-converting enzyme (ACE) inhibitors and bradykinin was investigated in isolated bovine and human… 
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