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fosinoprilat

Known as: L-Proline, 4-cyclohexyl-1-((hydroxy(4-phenylbutyl)phosphinyl)acetyl)-, trans-, SQ 27,519, fosinoprilic acid 
A phosphinic acid-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Fosinoprilat specifically and… Expand
National Institutes of Health

Papers overview

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2000
2000
AIMS To compare the serum pharmacokinetics of fosinoprilat with enalaprilat and lisinopril after 1 and 10 days of dosing with… Expand
2000
2000
  • M. Jemal, D. Mulvana
  • Journal of chromatography. B, Biomedical sciences…
  • 2000
  • Corpus ID: 35200795
A sensitive, specific, accurate and reproducible LC-MS-MS method was developed and validated for the simultaneous quantitation of… Expand
Highly Cited
1998
Highly Cited
1998
Combined inhibition of neutral endopeptidase (NEP) and angiotensin converting enzyme (ACE) produces cardiovascular effects… Expand
Highly Cited
1996
Highly Cited
1996
A soluble 67 kDa angiotensin-converting enzyme (ACE) has been purified by lisinopril-Sepharose affinity column chromatography… Expand
Highly Cited
1991
Highly Cited
1991
The specific neutral endopeptidase (NEP) inhibitor, SQ 29,072 (7-{2-(mercaptomethyl)-1-oxo-3-phenylpropyl]amino}heptanoic acid… Expand
Highly Cited
1991
Highly Cited
1991
We determined the relationship between cardiac angiotensin-converting enzyme (ACE) inhibition and anti-ischemic efficacy of… Expand
Highly Cited
1991
Highly Cited
1991
Single‐dose kinetics of fosinopril, a new phosphorus‐containing angiotensin‐converting enzyme inhibitor and its active diacid… Expand
1990
1990
The relative contribution of the gut, liver, and lung to the first-pass hydrolysis (bioactivation) of the orally administered… Expand
1989
1989
Summary: Fosinopril is the first member of a new chemical class of angiotensin I (AI) converting enzyme (ACE) inhibitors, the… Expand
Review
1989
Review
1989
There is increasing evidence that inhibition of tissue angiotensin converting enzyme (ACE) is important for the pharmacokinetics… Expand