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Fosinopril

Known as: (2S,4S)-4-Cyclohexyl-1-{2-[(2-methyl-1-propionyloxy-propoxy)-(4-phenyl-butyl)-phosphinoyl]-acetyl}-pyrrolidine-2-carboxylic acid, (2S,4S)-4-Cyclohexyl-1-[2-[(2-methyl-1-propanoyloxypropoxy)-(4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carboxylic acid, L-Proline, 4-cyclohexyl-1-(((2-methyl-1-(1-oxopropoxy)propoxy)(4-phenylbutyl)phosphinyl)acetyl)-, (1(S*(R*)),2alpha,4beta)- 
A phosphinic acid-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As an ester prodrug, fosinopril is… 
National Institutes of Health

Related topics

Related topics

29 relations
AngioedemaAngiotensin-Converting Enzyme Inhibitors [MoA]Congestive heart failureDecreased Blood Pressure [PE]

Broader (2)

Angiotensin-Converting Enzyme InhibitorsAntihypertensive Agents

Narrower (4)

Fosinopril SodiumMonoprilTenso Stopfosinoprilat

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Characterization of Fosinopril Natrium-hydroxypropyl-β-cyclodextrin Inclusion Complex
LAURA SBARCEA1*, LUCRETIA UDRESCU2, LIANA DRÃGAN1, CRISTINA TRANDAFIRESCU1, VIOREL SASCA3, PAUL BARVINSCHI4, MARIUS BOJITA5 1… 
2010
2010
Фармакоэкономические аспекты эффективности ингибиторов ангиотензин-превращающего фермента при артериальной гипертонии у пациентов с высоким сердечно-сосудистым риском
The paper presents pharmacological and economical aspects of in application of angiotensin converting enzyme inhibitors for… 
2009
2009
Inclusion compound of Fosinopril with β-cyclodextrin
Solid state interactions of bioactive substance (4-cyclohexyl-1-(2-((2-methyl-1-propanoyloxy-propoxy)-(4-phenyl- butyl)phosphoryl… 
2003
2003
Fosinopril-sodium and its degradation product analysis in monopril® tablets
The reversed-phase high-performance liquid chromatographic (RP-HPLC) method has been developed for the simultaneous determination… 
2000
2000
[Nephrotoxicity of high- and low-osmolar contrast media: Protective role of fosinopril or telmisartan in a rat model].
OBJECTIVE To compare the nephrotoxicity of high- and low-osmolar contrast media (HOCM and LOCM), and to determine the protective… 
1996
1996
[Antihypertensive effect of fosinopril in mild hypertension].
The aim of this double-blind randomized placebo-controlled study was to evaluate the antihypertensive and safety of fosinopril in… 
1996
1996
Effects of Fosinopril on Renal Function in Patients with Mild to Moderate Essential Hypertension
SummaryIn a 10-week double-blind randomised placebo-controlled trial, the efficacy, safety and effect on renal function of a… 
1994
1994
Effect of Fosinopril on Cardiac and Metabolic Parameters in Patients With NIDDM
OBJECTIVE To determine whether the angiotensin-converting enzyme (ACE) inhibitor fosinopril can favorably alter cardiac function… 
1993
1993
Angiotensin-Converting Enzyme Inhibitors and Chyluria
TO THE EDITOR: I read with interest the article by Keilani and colleagues [1], showing improvement of lipid abnormalities… 
1990
1990
Blood Pressure Lowering and Renal Hemodynamic Effects of Fosinopril in Conscious Animal Models
Summary: The blood pressure lowering and renal hemodynamic effects of fosinopril, the chemically novel inhibitor of angiotensin I…