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Fosinopril

Known as: (2S,4S)-4-Cyclohexyl-1-{2-[(2-methyl-1-propionyloxy-propoxy)-(4-phenyl-butyl)-phosphinoyl]-acetyl}-pyrrolidine-2-carboxylic acid, (2S,4S)-4-Cyclohexyl-1-[2-[(2-methyl-1-propanoyloxypropoxy)-(4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carboxylic acid, L-Proline, 4-cyclohexyl-1-(((2-methyl-1-(1-oxopropoxy)propoxy)(4-phenylbutyl)phosphinyl)acetyl)-, (1(S*(R*)),2alpha,4beta)- 
A phosphinic acid-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As an ester prodrug, fosinopril is… 
National Institutes of Health

Related topics

Related topics

29 relations
AngioedemaAngiotensin-Converting Enzyme Inhibitors [MoA]Congestive heart failureDecreased Blood Pressure [PE]

Broader (2)

Angiotensin-Converting Enzyme InhibitorsAntihypertensive Agents

Narrower (4)

Fosinopril SodiumMonoprilTenso Stopfosinoprilat

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Randomised controlled trial of leflunomide in the treatment of immunoglobulin A nephropathy
Aim:  To investigate the effect of leflunomide for treatment of immunoglobulin A (IgA) nephropathy. 
2006
2006
Effect of fosinopril in children with steroid-resistant idiopathic nephrotic syndrome
We aimed to test if fosinopril reduces urinary protein excretion and alleviates renal tubular damage in normotensive children… 
2005
2005
Effects of Fosinopril and Pravastatin on Carotid Intima-Media Thickness in Subjects With Increased Albuminuria
Background and Purpose— Elevated urinary albumin excretion (UAE) is associated with an increased carotid intima-media thickness… 
Highly Cited
2001
Highly Cited
2001
Mechanism of intestinal absorption and renal reabsorption of an orally active ace inhibitor: uptake and transport of fosinopril in cell cultures.
The objective of this study was to delineate the transepithelial transport mechanisms of fosinopril in cultured cell lines… 
Highly Cited
2000
Highly Cited
2000
Angiotensin-converting enzyme inhibitors downregulate tissue factor synthesis in monocytes.
Angiotensin-converting enzyme (ACE) inhibitors reduce the risk of recurrent myocardial infarction in patients with left… 
2000
2000
Cocaine, HIV, and their cardiovascular effects: is there a role for ACE-inhibitor therapy?
Review
1998
Review
1998
Calcium antagonists and cardiovascular risk in diabetes.
1997
1997
The alterations in insulin sensitivity during angiotensin converting enzyme inhibitor treatment are related to changes in the calcium/magnesium balance.
1996
1996
Fosinopril reduces ADP-induced platelet aggregation in hypertensive patients.
Platelets are intimately involved in atherosclerosis, and hypertension is a known risk factor for coronary artery disease. The… 
1993
1993
Comparative cytotoxicity of angiotensin-converting enzyme inhibitors in cultured rat hepatocytes.
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