Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Fosinopril

Known as: (2S,4S)-4-Cyclohexyl-1-{2-[(2-methyl-1-propionyloxy-propoxy)-(4-phenyl-butyl)-phosphinoyl]-acetyl}-pyrrolidine-2-carboxylic acid, (2S,4S)-4-Cyclohexyl-1-[2-[(2-methyl-1-propanoyloxypropoxy)-(4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carboxylic acid, L-Proline, 4-cyclohexyl-1-(((2-methyl-1-(1-oxopropoxy)propoxy)(4-phenylbutyl)phosphinyl)acetyl)-, (1(S*(R*)),2alpha,4beta)- 
A phosphinic acid-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As an ester prodrug, fosinopril is… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Cardiovascular events (CVEs) are the leading cause of death in chronic hemodialysis patients. Results of trials in non-end-stage… Expand
Highly Cited
2004
Highly Cited
2004
Background—Microalbuminuria is associated with increased risk of cardiovascular events. We assessed whether therapeutic… Expand
  • figure 1
  • table 1
  • table 2
  • table 3
  • table 4
Highly Cited
2002
Highly Cited
2002
Primary aldosteronism is a specifically treatable and potentially curable form of secondary hypertension. The aldosterone/plasma… Expand
Highly Cited
1999
Highly Cited
1999
OBJECTIVE To investigate the possible mechanisms of the antiatherosclerotic effects of the angiotensin-converting enzyme (ACE… Expand
  • figure 3
  • table 1
  • figure 4
  • figure 6
Highly Cited
1998
Highly Cited
1998
OBJECTIVE ACE inhibitors and calcium antagonists may favorably affect serum lipids and glucose metabolism. The primary aim of the… Expand
  • figure 1
  • table 1
  • table 2
  • table 3
  • figure 2
Highly Cited
1995
Highly Cited
1995
BACKGROUND Although chronic pressure overload may progress to left ventricular (LV) failure, the pathophysiology of this… Expand
Highly Cited
1995
Highly Cited
1995
We conducted this study to compare the effects of fosinopril versus atenolol on peripheral blood pressure, central arterial wave… Expand
Highly Cited
1994
Highly Cited
1994
BackgroundWe tested the hypotheses that long-term administration of the angiotensin-converting enzyme (ACE) inhibitor fosinopril… Expand
  • figure 1
  • table 1
  • figure 3
  • table 2
  • figure 4
Highly Cited
1992
Highly Cited
1992
Antihypertensive agents have been shown to exert inequivalent effects on glomerular injury in experimental renal disease models… Expand
  • figure 1
  • figure 3
  • figure 2
  • table 1
  • table 2
Highly Cited
1991
Highly Cited
1991
Single‐dose kinetics of fosinopril, a new phosphorus‐containing angiotensin‐converting enzyme inhibitor and its active diacid… Expand