Fosinopril

Known as: (2S,4S)-4-Cyclohexyl-1-{2-[(2-methyl-1-propionyloxy-propoxy)-(4-phenyl-butyl)-phosphinoyl]-acetyl}-pyrrolidine-2-carboxylic acid, (2S,4S)-4-Cyclohexyl-1-[2-[(2-methyl-1-propanoyloxypropoxy)-(4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carboxylic acid, L-Proline, 4-cyclohexyl-1-(((2-methyl-1-(1-oxopropoxy)propoxy)(4-phenylbutyl)phosphinyl)acetyl)-, (1(S*(R*)),2alpha,4beta)- 
A phosphinic acid-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As an ester prodrug, fosinopril is… (More)
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Cardiovascular events (CVEs) are the leading cause of death in chronic hemodialysis patients. Results of trials in non-end-stage… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Microalbuminuria is associated with increased risk of cardiovascular events. We assessed whether therapeutic… (More)
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2004
2004
BACKGROUND AND PURPOSE The Plaque Hypertension Lipid-Lowering Italian Study (PHYLLIS) tested whether (1) the angiotensin… (More)
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2002
2002
BACKGROUND The aim of this study is to compare the long-term effect of amlodipine and fosinopril in monotherapy or in combination… (More)
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Highly Cited
1999
Highly Cited
1999
OBJECTIVE To investigate the possible mechanisms of the antiatherosclerotic effects of the angiotensin-converting enzyme (ACE… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Altered vascular mechanics resulting from changes in collagen and integrins may influence resistance artery structure… (More)
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Highly Cited
1998
Highly Cited
1998
OBJECTIVE ACE inhibitors and calcium antagonists may favorably affect serum lipids and glucose metabolism. The primary aim of the… (More)
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1995
1995
We conducted this study to compare the effects of fosinopril versus atenolol on peripheral blood pressure, central arterial wave… (More)
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1992
1992
Antihypertensive agents have been shown to exert inequivalent effects on glomerular injury in experimental renal disease models… (More)
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