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formylmethionyl-leucyl-phenylalanine methyl ester

Known as: f-Met-Leu-Phe-OMe, L-Phenylalanine, N-(N-(N-formyl-L-methionyl)-L-leucyl)-, (SP-4-2)-, For-Met-Leu-Phe-OMe 
National Institutes of Health

Related topics

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2 relations

Broader (1)

N-Formylmethionine Leucyl-Phenylalanine
analogs & derivatives

Papers overview

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Highly Cited
2004
Highly Cited
2004
Inhibition of AKT survival pathway by a small molecule inhibitor in human endometrial cancer cells
The PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumour suppressor is mutated in 40–50% of human endometrial… 
Highly Cited
2000
Highly Cited
2000
Endothelial [Ca(2+)](i) signaling during transmigration of polymorphonuclear leukocytes.
Vascular endothelium plays an important role in regulating the transendothelial migration of polymorphonuclear leukocytes (PMNs… 
Highly Cited
1987
Highly Cited
1987
Human neutrophil laminin receptors: activation-dependent receptor expression.
Activated human polymorphonuclear leukocytes (PMN) isolated from peripheral blood specifically bind 125I-laminin after… 
Highly Cited
1985
Highly Cited
1985
Regulation of cellular function by products of lysosomal enzyme activity: elimination of human natural killer cells by a dipeptide methyl ester generated from L-leucine methyl ester by monocytes or…
L-Leucine methyl ester (Leu-OMe) is a lysosomotropic compound that irreversibly removes natural killer cell (NK) function from… 
Highly Cited
1984
Highly Cited
1984
Stimulus response coupling in the human neutrophil. I. Kinetic analysis of changes in calcium permeability.
Highly Cited
1983
Highly Cited
1983
Altered polymorphonuclear leukocyte responses in psoriasis: chemotaxis and degranulation
Chemotactic activities of circulating polymorphonuclear leukocytes (PMN) were determined in twenty patients with psoriasis and… 
Highly Cited
1982
Highly Cited
1982
Membrane activity and topography of F-Met-Leu-Phe-Treated polymorphonuclear leukocytes. Acute and sustained responses to chemotactic peptide.
The chemotactic peptide N-formylmethionyl-leucyl-phenylalanine (f-Met-Leu-Phe) causes a dramatic stimulation of membrane ruffling… 
Highly Cited
1981
Highly Cited
1981
Deactivation of human neutrophil chemotaxis by chemoattractants: effect on receptors for the chemotactic factor f-Met-Leu-Phe.
Normal human peripheral blood PMN were exposed to varying concentrations of partially purified chemotactic complement fragments… 
Highly Cited
1979
Highly Cited
1979
Involvement of membrane calcium in the response of rabbit neutrophils to chemotactic factors as evidenced by the fluorescence of chlorotetracycline
We have utilized the fluorescent chelate probe chlorotetracycline to investigate the possible involvement of membrane calcium in… 
Highly Cited
1977
Highly Cited
1977
Interaction of chemotactic factors with human macrophages: induction of transmembrane potential changes
The electrophysiology of chemotactic factor interaction with cultured human macrophages was investigated with standard… 
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