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N-Formylmethionine Leucyl-Phenylalanine

Known as: L-Phenylalanine, N-(N-(N-formyl-L-methionyl)-L-leucyl)-, fMLP (formyl-met-leu-phe), N Formylmethionine Leucyl Phenylalanine 
A formylated tripeptide originally isolated from bacterial filtrates that is positively chemotactic to polymorphonuclear leucocytes, and causes them… Expand
National Institutes of Health

Related topics

Related topics

22 relations

Broader (2)

Chemotactic FactorsPeptides

Narrower (12)

F-Met-Leu-PheFormylmethionyl PeptideN-formyl-methionyl-leucyl-phenylalanyl-phenylalanineN-formylmethionine-thioamide-leucyl-phenylalanine methyl ester
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FPR1 geneIn Bloodagonistsanalogs & derivatives
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
On the origin of biochemistry at an alkaline hydrothermal vent
A model for the origin of biochemistry at an alkaline hydrothermal vent has been developed that focuses on the acetyl-CoA (Wood… Expand
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Highly Cited
2004
Highly Cited
2004
Inflammation- and ischemia-induced shedding of venular glycocalyx.
Alterations in the composition of the glycocalyx of venular endothelium in postcapillary venules (rat mesentery) were explored in… Expand
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Highly Cited
2000
Highly Cited
2000
Enhanced release of superoxide from polymorphonuclear neutrophils in obstructive sleep apnea. Impact of continuous positive airway pressure therapy.
Obstructive sleep apnea (OSA) is associated with increased cardiovascular morbidity and mortality. Free oxygen radicals have been… Expand
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Highly Cited
1999
Highly Cited
1999
A Seven-transmembrane, G Protein–coupled Receptor, FPRL1, Mediates the Chemotactic Activity of Serum Amyloid A for Human Phagocytic Cells
We have previously reported (Badolato, R., J.M. Wang, W.J. Murphy, A.R. Lloyd, D.F. Michiel, L.L. Bausserman, D.J. Kelvin, and J… Expand
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Highly Cited
1998
Highly Cited
1998
The Oxazolidinone Linezolid Inhibits Initiation of Protein Synthesis in Bacteria
ABSTRACT The oxazolidinones represent a new class of antimicrobial agents which are active against multidrug-resistant… Expand
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Highly Cited
1997
Highly Cited
1997
Covalent modification of the active site threonine of proteasomal beta subunits and the Escherichia coli homolog HslV by a new class of inhibitors.
The proteasome is a multicatalytic protease complex that plays a key role in diverse cellular functions. The peptide vinyl… Expand
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Highly Cited
1996
Highly Cited
1996
Identification of Defensin-1, Defensin-2, and CAP37/Azurocidin as T-cell Chemoattractant Proteins Released from Interleukin-8-stimulated Neutrophils (*)
Reports that interleukin-8 (IL-8) induces the infiltration of neutrophils followed by T-cells into injection sites led us to… Expand
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Highly Cited
1993
Highly Cited
1993
Inhibition of apoptosis and prolongation of neutrophil functional longevity by inflammatory mediators.
Neutrophil apoptosis leads to macrophage ingestion of intact senescent neutrophils. This may represent a neutrophil removal… Expand
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Highly Cited
1992
Highly Cited
1992
A mechanism for the antiinflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion…
Corticosteroids are the preeminent antiinflammatory agents although the molecular mechanisms that impart their efficacy have not… Expand
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Highly Cited
1985
Highly Cited
1985
Thrombin stimulates the adherence of neutrophils to human endothelial cells in vitro.
Highly purified human thrombin stimulates the adherence of polymorphonuclear leukocytes (PMNs) to vascular endothelial cells (EC… Expand
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