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flavin-containing monooxygenase activity

Known as: FMO3, FMO1, FMO-I 
National Institutes of Health

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6 relations
Dimethylaniline Monooxygenase [N-Oxide-Forming] 3, humandimethylaniline monooxygenase (N-oxide forming) activityflavin-containing monooxygenase 2flavin-containing monooxygenase 3

Papers overview

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2012
2012
Metabolism and Pharmacokinetics of the Anti-Tuberculosis Drug Ethionamide in a Flavin-Containing Monooxygenase Null Mouse
Multiple drug resistance (MDR) in Mycobacterium tuberculosis (mTB), the causative agent for tuberculosis (TB), has led to… 
2009
2009
Enantioselective in‐line and off‐line CE methods for the kinetic study on cimetidine and its chiral metabolites with reference to flavin‐containing monooxygenase genetic isoforms
An in‐line screening and an off‐line chiral CE method were developed to determine the stereoselectivity of flavin‐containing… 
1998
1998
Identification of amino acid residues associated with modulation of flavin-containing monooxygenase (FMO) activity by imipramine: structure/function studies with FMO1 from pig and rabbit.
The activity of the flavin-containing monooxygenase (FMO) can be modulated by a number of nitrogen-containing compounds in a… 
1997
1997
Induction of flavin-containing monooxygenase (FMO1) by a polycyclic aromatic hydrocarbon, 3-methylcholanthrene, in rat liver.
1997
1997
Molecular cloning of mouse liver flavin containing monooxygenase (FMO1) cDNA and characterization of the expression product: metabolism of the neurotoxin, 1,2,3,4-tetrahydroisoquinoline (TIQ).
A mouse liver cDNA clone, MFMO1, coding for a flavin-containing monooxygenase (FMO) was isolated. This cDNA clone encoded a… 
1996
1996
Xenobiotic biotransforming enzymes in the central nervous system: an isoform of flavin-containing monooxygenase (FMO4) is expressed in rabbit brain.
1995
1995
The flavin-containing monooxygenases in rat liver: evidence for the expression of a second form different from FMO1.
A second form of rat liver FMO, FMO-A, was separated and purified by chromatography on Blue Sepharose Fast flow 6. This FMO-A is… 
1994
1994
Isolation and structure of a third form of liver microsomal flavin monooxygenase.
Flavin-containing monooxygenases (FMOs) catalyze NADPH-dependent oxygenation of nucleophilic nitrogen, sulfur, and phosphorous… 
Highly Cited
1992
Highly Cited
1992
Cloning, primary sequence and chromosomal localization of human FMO2, a new member of the flavin-containing mono-oxygenase family.
We have previously reported the cloning of cDNAs for a flavin-containing mono-oxygenase (FMO) of man, designated FMO1 [Dolphin… 
1992
1992
NADPH-dependent oxidation of reduced ebselen, 2-selenylbenzanilide, and of 2-(methylseleno)benzanilide catalyzed by pig liver flavin-containing monooxygenase.
The selenazole ring-opened metabolites of ebselen, 2-selenylbenzanilide and 2-(methylseleno)benzanilide, are substrates for… 
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