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Dimethylaniline Monooxygenase [N-Oxide-Forming] 3, human

Known as: Dimethylaniline Oxidase 3, FMO Form 2, Flavin-Containing Monooxygenase-3 
Dimethylaniline monooxygenase [N-oxide-forming] 3 (532 aa, ~60 kDa) is encoded by the human FMO3 gene. This protein is involved in the oxygenation… 
National Institutes of Health

Related topics

Related topics

11 relations
Drug Metabolism InductionEnzyme GeneFMO3 geneLiver parenchyma

Broader (1)

flavin-containing monooxygenase 3

Papers overview

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2017
2017
The Oxidation of Hydrophobic Aromatic Substrates by Using a Variant of the P450 Monooxygenase CYP101B1
The cytochrome P450 monooxygenase CYP101B1, from a Novosphingobium bacterium is able to bind and oxidise aromatic substrates but… 
2017
2017
Identification of human flavin-containing monooxygenase 3 substrates by a colorimetric screening assay.
2012
2012
Entrapment of human flavin-containing monooxygenase 3 in the presence of gold nanoparticles: TEM, FTIR and electrocatalysis.
2006
2006
Experimental approaches to studies on drug metabolism and drug interactions in man: interaction of acyclic nucleoside phosphonates with human liver cytochromes P450 and flavin-containing…
OBJECTIVES To determine a possible influence of acyclic nucleoside phosphonates on FMO3 and CYP activity at molecular level in… 
2003
2003
Deleterious mutations in the flavin-containing monooxygenase 3 (FMO3) gene causing trimethylaminuria.
The primary genetic form of trimethylaminuria (TMAU) is caused by inherited defects in the flavin-containing monooxygenase 3… 
2002
2002
Thiourea toxicity in mouse C3H/10T1/2 cells expressing human flavin-dependent monooxygenase 3.
2002
2002
A mutation in the flavin-containing monooxygenase 3 gene and its effects on catalytic activity for N-oxidation of trimethylamine in vitro.
To clarify the mutation of the flavin-containing monooxygenase (FMO) 3 gene causing fish-odor syndrome, we analyzed the FMO3 gene… 
Highly Cited
2000
Highly Cited
2000
Compound heterozygosity for missense mutations in the flavin-containing monooxygenase 3 (FM03) gene in patients with fish-odour syndrome.
Fish-odour syndrome is a highly unpleasant disorder of hepatic trimethylamine (TMA) metabolism characterized by a body odour… 
1995
1995
Properties of a soluble propene monooxygenase from Mycobacterium sp. (strain M156)
Mycobacterium sp. strain M156, isolated on propene as sole carbon and energy source, possessed NAD(P)H-linked propene… 
1977
1977
An improved radiochemical assay for benzo(a)pyrene monooxygenase.
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