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FMO3 gene

Known as: FLAVIN-CONTAINING MONOOXYGENASE 3, FMO3, flavin containing monooxygenase 3 
This gene is involved in the oxidation of xenobiotics.
National Institutes of Health

Related topics

Related topics

5 relations
Dimethylaniline Monooxygenase [N-Oxide-Forming] 3, humanDrug Metabolism InductionOxidation-Reductionflavin-containing monooxygenase 3

Papers overview

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2019
2019
Genetic variants of flavin-containing monooxygenase 3 (FMO3) derived from Japanese subjects with the trimethylaminuria phenotype and whole-genome sequence data from a large Japanese database.
2019
2019
Non-synonymous genetic variants of flavin-containing monooxygenase 3 (FMO3) in cynomolgus macaques.
2008
2008
Complex mechanism underlying transcriptional control of the haplotyped flavin-containing monooxygenase 3 (FMO3) gene in Japanese: different regulation between mutations in 5'-upstream distal region…
We reported the human flavin-containing monooxygenase 3 (FMO3) haplotypes (Pharmacogenet. Genomics: 17, 827, 2007). The objective… 
2007
2007
Allele and genotype frequencies of polymorphic FMO3 gene in two genetically distinct populations
The aims of this study were to analyze flavin‐containing monooxygenase 3 (FMO3) polymorphisms and allele and genotype frequencies… 
2007
2007
Stop codon mutations in the flavin-containing monooxygenase 3 (FMO3) gene responsible for trimethylaminuria in a Japanese population.
2006
2006
Bioactivation of N-substituted N′-(4-imidazole-ethyl)thioureas by human FMO1 and FMO3
Enzyme kinetic parameters of the bioactivation of thiourea-containing compounds by human flavin-containing monooxygenase enzymes… 
Highly Cited
2005
Highly Cited
2005
Discovery of Novel Flavin-Containing Monooxygenase 3 (FMO3) Single Nucleotide Polymorphisms and Functional Analysis of Upstream Haplotype Variants
The flavin-containing monooxygenases (FMOs) are important for xenobiotic metabolism. FMO3, the predominant FMO enzyme in human… 
2003
2003
Two novel single nucleotide polymorphisms (SNPs) of the FMO3 gene in Japanese.
We sequenced all exons and exon-intron junctions of the flavin-containing monooxygenase 3 (FMO3) gene from 27 Japanese… 
2001
2001
Cloning, sequencing, tissue distribution, and heterologous expression of rat flavin-containing monooxygenase 3.
The sequence of rat FMO3 was obtained by RT-PCR and 5'/3' terminal extension. Complete cDNA was amplified, cloned, and sequenced… 
2000
2000
A novel mutation in the flavin-containing monooxygenase 3 gene, FM03, that causes fish-odour syndrome: activity of the mutant enzyme assessed by proton NMR spectroscopy.
We have previously shown that primary trimethylaminuria, or fish-odour syndrome, is caused by an inherited defect in the flavin… 
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