filaggrin

Known as: Epidermal Filaggrin, Stratum corneum basic protein, filagrin 
Filaggrin (4061 aa, ~435 kDa) is encoded by the human FLG gene. This protein is involved in the structure of intermediate filaments.
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Filaggrin has a key structural and functional role in the epidermis with important impact on the homeostasis of the skin… (More)
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2012
2012
Atopic eczema and psoriasis are common skin diseases. While it is well established that the pathogenesis of these diseases varies… (More)
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Review
2012
Review
2012
Filaggrin is a key component of the epidermal differentiation complex of the stratum corneum in the epidermal layer of human skin… (More)
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Highly Cited
2010
Highly Cited
2010
Loss-of-function mutations in the filaggrin gene are associated with ichthyosis vulgaris and atopic dermatitis. To investigate… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Atopic dermatitis (AD) is a chronic inflammatory skin disease that is characterized by a defective skin barrier… (More)
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Highly Cited
2009
Highly Cited
2009
Filaggrin is a component of the cornified cell envelope and the precursor of free amino acids acting as a natural moisturizing… (More)
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Highly Cited
2000
Highly Cited
2000
IgG anti-filaggrin autoantibodies (AFA) are the most specific serological markers of rheumatoid arthritis (RA). They include the… (More)
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Highly Cited
2000
Highly Cited
2000
Flaky tail (gene symbol ft) is an autosomal recessive mutation in mice that results in a dry, flaky skin, and annular tail and… (More)
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1996
1996
The upper layers of mammalian epidermis contain citrulline-containing proteins formed by enzymatic deimination of arginine… (More)
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Highly Cited
1995
Highly Cited
1995
The so-called antikeratin antibodies (AKA) and the antiperinuclear factor (APF) are the most specific serological markers of RA… (More)
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