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Elafin is induced in epidermis in skin disorders with dermal neutrophilic infiltration: interleukin-1 beta and tumour necrosis factor-alpha stimulate its secretion in vitro.
TLDR
It is suggested that inflammatory mediators such as IL-1 beta or TNF-alpha secreted by dermal neutrophils may be involved in overexpression of elafin in keratinocytes; this could protect the epidermis from degradation by der mal neutrophil infiltration.
Photodynamic therapy of acne vulgaris with topical δ‐aminolaevulinic acid and incoherent light in Japanese patients
Background  Photodynamic therapy (PDT) is useful for treatment of epidermal neoplasia but may also have a role in the treatment of inflammatory dermatoses.
Photodynamic therapy for acne vulgaris with topical 5-aminolevulinic acid.
TLDR
After obtaining informed consent, the patient was treated with topical 5-aminolevulinic acid photodynamic therapy (ALA-PDT) and the affected area did not present any new acne during a follow-up period of 8 months.
Systemic phaeohyphomycosis caused by Exophiala dermatitidis
TLDR
A case of systemic phaeohyphomycosis due to Exophiala dermatitidis in a 24‐year-old man, who complained of diplopia and a slight heaviness in the head two years later, and died a year later.
Elastin peptides induce migration and terminal differentiation of cultured keratinocytes via 67 kDa elastin receptor in vitro: 67 kDa elastin receptor is expressed in the keratinocytes eliminating
TLDR
Elastin is a potent inducer of migration and terminal differentiation of cultured keratinocytes, which is mediated by the 67 kDa elastin receptor, which was specifically expressed in the epidermis immediately surrounding the elastic materials that were being eliminated.
Processing of cathepsins L, B and D in psoriatic epidermis
TLDR
Results suggest that cathepsins L, B and D in forms activated to a variable extent may be involved in the pathology of psoriasis.
Elafin is induced in epidermis in skin disorders with dermal neutrophilic infiltration: interleukin‐1β and tumour necrosis factor‐α stimulate its secretion in vitro
TLDR
Anti‐elafin antibody showed a strong reaction with the subcorneal region of the epidermis in patients with Behçet's syndrome, Sweet’s syndrome, pyoderma gangrenosum, cutaneous allergic vasculitis and acute bacterial infection (cellulitis), but showed no reaction in skin from patients with dermal lymphocyte infiltration such as is seen in chronic prurigo and discoid lupus erythematosus.
Coordinate expression of membrane type-matrix metalloproteinases-2 and 3 (MT2-MMP and MT3-MMP) and matrix metalloproteinase-2 (MMP-2) in primary and metastatic melanoma cells.
TLDR
The colocalization of MT2,3-MMP and MMP-2 in nodular and metastatic melanoma cells suggests that MT-M MPs and M MP-2 co-operate in the invasive and metastasis process of melanoma Cells.
Granulocyte and macrophage colony-stimulating factors stimulate proliferation of human keratinocytes
TLDR
This study demonstrated that Gand M-CSFs had stimulatory effects on keratinocyte growth in culture, indicating that they may be potential autocrine growth factors for keratinocytes, since these two CSFs are produced by Keratinocytes as well as by immune cells.
Cathepsin B and D expression in squamous cell carcinoma
TLDR
Coexistence and localization of active mature forms of cathepsins B and D suggests that cooperation between tbe two enzymes may play an important part in invasion of SCC.
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