Skip to search formSkip to main contentSkip to account menu

FLG gene

Known as: Filaggrin Gene, FLG, FILAGGRIN 
This gene is involved in intermediate filament structure.
National Institutes of Health

Related topics

Related topics

1 relation
filaggrin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Molecular Pathogenesis of Genetic and Inherited Diseases Flaky Tail Mouse Denotes Human Atopic Dermatitis in the Steady State and by Topical Application with Dermatophagoides pteronyssinus Extract
From the Department of Dermatology,* and the Center for Innovation in Immunoregulative Technology and Therapeutics, Graduate… 
Highly Cited
2008
Highly Cited
2008
Long-Range Enhancer Associated with Chromatin Looping Allows AP-1 Regulation of the Peptidylarginine Deiminase 3 Gene in Differentiated Keratinocyte
Transcription control at a distance is a critical mechanism, particularly for contiguous genes. The peptidylarginine deiminases… 
Highly Cited
2004
Highly Cited
2004
FOXN1 is critical for onycholemmal terminal differentiation in nude (Foxn1) mice.
Nude mice have a mutation in the transcription factor Foxn1(nu), resulting in downregulation of hair keratins. Although hair… 
Review
2003
Review
2003
Advances in B-cell epitope analysis of autoantigens in connective tissue diseases.
Highly Cited
1997
Highly Cited
1997
Definition by specific antisense oligonucleotides of a role for protein kinase Cα in expression of differentiation markers in normal and neoplastic mouse epidermal keratinocytes
Epidermal keratinocyte differentiation is a tightly regulated, stepwise process that requires protein kinase C (PKC) activation… 
Highly Cited
1995
Highly Cited
1995
Cholesterol sulfate activates multiple protein kinase C isoenzymes and induces granular cell differentiation in cultured murine keratinocytes.
The accumulation of cholesterol sulfate (CS) in differentiating keratinocytes coincides with the expression of protein kinase C… 
Highly Cited
1993
Highly Cited
1993
Analysis of the cornified cell envelope in lamellar ichthyosis.
BACKGROUND Loricrin and involucrin are major precursor proteins to the cornified cell envelope expressed late in epidermal… 
Highly Cited
1990
Highly Cited
1990
Phenotypes and interactions of human melanocytes and keratinocytes in an epidermal reconstruction model.
The morphologic and antigenic phenotype of normal human melanocytes and keratinocytes was investigated in monolayer and 3… 
Highly Cited
1989
Highly Cited
1989
Identification of proteolytic cleavage sites in the conversion of profilaggrin to filaggrin in mammalian epidermis.
Highly Cited
1984
Highly Cited
1984
High-molecular-weight precursor of epidermal filaggrin and hypothesis for its tandem repeating structure.
Filaggrin is a histidine-rich protein that is intimately involved in mammalian epidermal keratinization. Using a combination of… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)