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A comprehensive guide for the accurate classification of murine hair follicles in distinct hair cycle stages.
This guide should become a useful tool when screening new mouse mutants or mice treated with pharmaceuticals for discrete morphologic abnormalities of hair follicle cycling in a highly reproducible, easily applicable, and quantifiable manner.
The biology of hair follicles.
Progress in understanding of the biology and pathology of hair follicles should lead to more effective therapies for disorders of hair growth, and few drugs that are effective for these purposes are available.
What controls hair follicle cycling?
The following contributions are designed to stimulate the discussion of the chronobiological control system that cyclically drives the hair follicle through dramatic remodelling processes between phases of growth, regression, and relative resting.
The Hair Follicle as a Dynamic Miniorgan
Sonic hedgehog signaling is essential for hair development
Corticotropin releasing hormone and proopiomelanocortin involvement in the cutaneous response to stress.
- A. Slominski, J. Wortsman, T. Luger, R. Paus, S. Solomon
- Biology, MedicinePhysiological reviews
- 1 July 2000
Cutaneous expression of the CRH/POMC system is highly organized, encoding mediators and receptors similar to the hypothalamic-pituitary-adrenal (HPA) axis, that in the skin is expressed as a highly localized response which neutralizes noxious stimuli and attendant immune reactions.
Molecular principles of hair follicle induction and morphogenesis
The morphological characteristics, major underlying principles and molecular key players that control HF development are introduced and a corresponding working hypothesis is synthesized.
Controls of hair follicle cycling.
This review has used Chase as the model and tried to put the adult hair follicle growth cycle in perspective, and hopes that this work will serve as an introduction to basic biologists who are looking for a defined biological system that illustrates many of the challenges of modern biology.
IL-15/IL-15 receptor biology: a guided tour through an expanding universe.
Noggin is a mesenchymally derived stimulator of hair-follicle induction
As a crucial mesenchymal signal that stimulates hair-follicle induction, Noggin operates through antagonistic interactions with BMP-4, which result in upregulation of the transcription factor Lef-1 and the cell-adhesion molecule NCAM, as well as through BMP4-independent down regulation of the 75 kD neurotrophin receptor in the developing hair follicle.