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[Psoriasis: pathogenesis and treatment].
- M. Heenen
- Revue medicale de Bruxelles
Psoriasis is a T-cell mediated disease. Its pathogenesis is linked to the activation of T-cells by antigen-presenting cells and secretion of cytokines able to modulate keratinocyte proliferation and… Expand
Iron chelators inhibit the growth and induce the apoptosis of Kaposi's sarcoma cells and of their putative endothelial precursors.
- T. Simonart, C. Degraef, +7 authors M. Heenen
- Biology, Medicine
- The Journal of investigative dermatology
- 1 November 2000
Iron is suspected to be involved in the induction and/or progression of various human tumors. More particularly, iron may be involved in the pathogenesis of Kaposi's sarcoma, a tumor of probable… Expand
Apoptosis in Established and Healing Psoriasis
Background: Previous studies have described apoptosis in the stratum granulosum and in the stratum corneum, but not in the germinative compartment in normal skin. In psoriasis, an increased epidermal… Expand
Nicolau syndrome following diclofenac administration
in three and moderate in three cases. Su et al. recently described CD117 expression in 20 out of 21 Merkel cell carcinomas in a similar distribution, but whilst nearly all of their cases expressed… Expand
Clinical efficacy and safety comparison of adapalene gel and tretinoin gel in the treatment of acne vulgaris: Europe and U.S. multicenter trials.
- W. Cunliffe, R. Caputo, +21 authors M. Verschoore
- Journal of the American Academy of Dermatology
- 1 June 1997
BACKGROUND Adapalene is a new chemical entity that exhibits tretinoin-like activities in the terminal differentiation process. OBJECTIVE We evaluated a dose range effect of two concentrations of… Expand
Three percent diclofenac in 2.5% hyaluronan gel in the treatment of actinic keratoses: a meta-analysis of the recent studies
- D. Pirard, P. Vereecken, C. Mélot, M. Heenen
- Archives of Dermatological Research
- 19 October 2005
Three percent diclofenac in 2.5% hyaluronan gel (DHA) is approved by the Food and Drug Administration (FDA) in the treatment of actinic keratoses (AK). We conducted a meta-analysis of the few… Expand
Value of standard laboratory tests for the early recognition of group A beta-hemolytic streptococcal necrotizing fasciitis.
- T. Simonart, J. Simonart, +9 authors M. Heenen
- Clinical infectious diseases : an official…
The laboratory data for 17 patients with group A beta-hemolytic streptococcal necrotizing fasciitis (GAS NF) were compared with data for 145 patients hospitalized for cellulitis during the same… Expand
Anti-Tumor Necrosis Factor Alpha-Induced Psoriasiform Eruptions: Three Further Cases and Current Overview
The increasing use of anti-TNF-α agents led to a better knowledge of their side effects. Among the cutaneous reactions, psoriasiform eruptions are increasingly described. We encountered 3 further… Expand
Evaluation of the prognostic significance of serum galectin-3 in American Joint Committee on Cancer stage III and stage IV melanoma patients
Galectin-3 (Gal-3) is a member of the &bgr;-galactoside-binding lectins family and has been implicated in angiogenesis, tumor invasion, and metastatic process in vitro and in vivo. As we showed… Expand
Evaluation of extensive initial staging procedure in intermediate/high‐risk melanoma patients
- P. Vereecken, M. Laporte, M. Pétein, E. Steels, M. Heenen
- Journal of the European Academy of Dermatology…
- 1 January 2005
Introduction Early diagnosis and treatment of metastases have been shown to improve overall survival of melanoma patients. The purpose of this study was to evaluate the impact of extensive initial… Expand