Intermediate Filaments

Known as: Filament, Intermediate, Filaments, Intermediate, Intermediate filament 
A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic… (More)
National Institutes of Health

Related topics

Related topics

18 relations
CytokeratinCytokeratin filamentsCytoskeletonKeratin
(More)

Narrower (3)

Cytoplasmic intermediate filamentNeurofilamentsNuclear lamin

Broader (2)

Cytoskeletal FilamentsIntermediate filament cytoskeleton

Papers overview

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Highly Cited
2010
Highly Cited
2010
Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia
Invasive cancer cells are believed to breach the basement membrane (BM) using specialized protrusions called invadopodia. We… (More)
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Review
2009
Review
2009
Introducing intermediate filaments: from discovery to disease.
It took more than 100 years before it was established that the proteins that form intermediate filaments (IFs) comprise a unified… (More)
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Review
2007
Review
2007
Intermediate filaments: from cell architecture to nanomechanics
Intermediate filaments (IFs) constitute a major structural element of animal cells. They build two distinct systems, one in the… (More)
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Review
2004
Review
2004
Intermediate filaments mediate cytoskeletal crosstalk
Intermediate filaments, actin-containing microfilaments and microtubules are the three main cytoskeletal systems of vertebrate… (More)
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Review
2003
Review
2003
Molecular architecture of intermediate filaments.
Together with microtubules and actin microfilaments, approximately 11 nm wide intermediate filaments (IFs) constitute the… (More)
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Review
2000
Review
2000
Are desmosomes more than tethers for intermediate filaments?
Desmosomes are intercellular adhesive junctions that anchor intermediate filaments at membrane-associated plaques in adjoining… (More)
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Highly Cited
1997
Highly Cited
1997
Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure.
We report here that living cells and nuclei are hard-wired such that a mechanical tug on cell surface receptors can immediately… (More)
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Highly Cited
1997
Highly Cited
1997
Caspase Cleavage of Keratin 18 and Reorganization of Intermediate Filaments during Epithelial Cell Apoptosis
Keratins 8 (K8) and 18 (K18) are major components of intermediate filaments (IFs) of simple epithelial cells and tumors derived… (More)
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Review
1996
Review
1996
Neuronal intermediate filaments.
Neurofilaments (NFs) are the most abundant structural components in large-diameter myelinated axons. Assembled as obligate… (More)
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Highly Cited
1980
Highly Cited
1980
Intermediate filaments as mechanical integrators of cellular space
Five chemically distinct classes of intermediate filaments can be identified within higher eukaryotic cells. Each class is… (More)
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