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fenobam

National Institutes of Health

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Broader (1)

Imidazoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
The metabotropic glutamate receptor 5 radioligand [11C]AZD9272 identifies unique binding sites in primate brain
Review
2014
Review
2014
Use of metabotropic glutamate 5-receptor antagonists for treatment of levodopa-induced dyskinesias.
2014
2014
Combined fenobam and amantadine treatment promotes robust antidyskinetic effects in the 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP)‐lesioned primate model of Parkinson's disease
Amantadine, an N‐methyl‐D‐aspartate glutamate receptor antagonist, is currently the only pharmacological treatment for levodopa… 
2012
2012
Orthosteric and allosteric drug binding sites in the Caenorhabditis elegans mgl-2 metabotropic glutamate receptor
Highly Cited
2011
Highly Cited
2011
CTEP: A Novel, Potent, Long-Acting, and Orally Bioavailable Metabotropic Glutamate Receptor 5 Inhibitor
The metabotropic glutamate receptor 5 (mGlu5) is a glutamate-activated class C G protein-coupled receptor widely expressed in the… 
Review
2010
Review
2010
Cognitive effects of Group I metabotropic glutamate receptor ligands in the context of drug addiction.
Highly Cited
2009
Highly Cited
2009
The Metabotropic Glutamate Receptor Subtype 5 Antagonist Fenobam Is Analgesic and Has Improved in Vivo Selectivity Compared with the Prototypical Antagonist 2-Methyl-6-(phenylethynyl)-pyridine
Metabotropic glutamate receptor subtype 5 (mGlu5) has been demonstrated to play a role in the modulation of numerous nociceptive… 
Review
1983
Review
1983
Novel non-benzodiazepine anxiolytics
Highly Cited
1982
Highly Cited
1982
Differential antagonism of the anticonflict effects of typical and atypical anxiolytics.
Highly Cited
1982
Highly Cited
1982
Treatment of anxiety using fenobam (a nonbenzodiazepine) in a double-blind standard (diazepam) placebo-controlled study.
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