FAQ

ezrin

Known as: Villin-2, p81, Cytovillin 
Ezrin protein (586 aa, ~69 kDa) is encoded by the human EZR gene. This protein plays a role in mediating the interaction of the plasma membrane with… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2018
05019862018

Related topics

Related topics

10 relations
Cell MovementCytokinesisCytoskeletal GeneCytoskeleton
(More)

Broader (1)

Cytoskeletal Proteins

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
ezrin
Migration, Cell
Muscle Contraction
Cytokinesis
Cell Movement
Cytoskeleton

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis
Metastatic cancers, once established, are the primary cause of mortality associated with cancer. Previously, we used a genomic… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Phosphoinositide binding and phosphorylation act sequentially in the activation mechanism of ezrin
Ezrin, a membrane-actin cytoskeleton linker, which participates in epithelial cell morphogenesis, is held inactive in the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes
Ezrin, radixin, and moesin (ERM) regulate cortical morphogenesis and cell adhesion by connecting membrane adhesion receptors to… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Rho-Kinase Phosphorylates COOH-terminal Threonines of Ezrin/Radixin/Moesin (ERM) Proteins and Regulates Their Head-to-Tail Association
The ezrin/radixin/moesin (ERM) proteins are involved in actin filament/plasma membrane interaction that is regulated by Rho. We… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Identification of EBP50: A PDZ-containing Phosphoprotein that Associates with Members of the Ezrin-Radixin-Moesin Family
Members of the ezrin-radixin-moesin (ERM) family of membrane-cytoskeletal linking proteins have NH2- and COOH-terminal domains… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Ezrin Is an Effector of Hepatocyte Growth Factor–mediated Migration and Morphogenesis in Epithelial Cells
The dissociation, migration, and remodeling of epithelial monolayers induced by hepatocyte growth factor (HGF) entail… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway
The ERM proteins, ezrin, radixin, and moesin, are involved in the actin filament/plasma membrane interaction as cross-linkers… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Ezrin has a COOH-terminal actin-binding site that is conserved in the ezrin protein family
Ezrin, previously also known as cytovillin, p81, and 80K, is a cytoplasmic protein enriched in microvilli and other cell surface… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
1993
Highly Cited
1993
Ezrin contains cytoskeleton and membrane binding domains accounting for its proposed role as a membrane-cytoskeletal linker
Ezrin, a widespread protein present in actin-containing cell-surface structures, is a substrate of some protein tyrosine kinases… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1989
Highly Cited
1989
Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factor
Addition of EGF to human carcinoma A-431 cells is known to induce membrane ruffling after approximately 2 min (Chinkers, M., J. A… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?