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eukaryotic translation initiation factor 2 complex location

Known as: eIF-2, eIF2, eukaryotic translation initiation factor 2 complex 
Complex of three heterogeneous polypeptide chains, that form a ternary complex with initiator methionyl-tRNA and GTP. This ternary complex binds to… 
National Institutes of Health

Related topics

Related topics

3 relations
EIF2S1 wt AlleleEIF2S3 geneEukaryotic Initiation Factor-2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
eIF2B is a decameric guanine nucleotide exchange factor with a γ2ε2 tetrameric core
eIF2B facilitates and controls protein synthesis in eukaryotes by mediating guanine nucleotide exchange on its partner eIF2. We… 
Highly Cited
2000
Highly Cited
2000
Identification of Caspase 3-mediated Cleavage and Functional Alteration of Eukaryotic Initiation Factor 2α in Apoptosis*
Induction of apoptosis in a variety of cell types leads to inhibition of protein synthesis. Recently, the cleavage of eukaryotic… 
Review
1991
Review
1991
Eukaryotic initiation factors eIF-2 and eIF-3: interactions, structure and localization in ribosomal initiation complexes.
Highly Cited
1987
Highly Cited
1987
Regulation of polypeptide chain initiation in Chinese hamster ovary cells with a temperature-sensitive leucyl-tRNA synthetase. Changes in phosphorylation of initiation factor eIF-2 and in the…
Highly Cited
1987
Highly Cited
1987
Inhibition of rabbit reticulocyte lysate protein synthesis by heavy metal ions involves the phosphorylation of the alpha-subunit of the eukaryotic initiation factor 2.
Highly Cited
1982
Highly Cited
1982
Phosphorylation inhibits guanine nucleotide exchange on eukaryotic initiation factor 2
There is extensive evidence that protein synthesis in reticulocyte lysates is inhibited during haem deficiency because of… 
Highly Cited
1982
Highly Cited
1982
Regulation of protein synthesis in vesicular stomatitis virus-infected mouse L-929 cells by decreased protein synthesis initiation factor 2 activity
Infection of mouse L-cell spinner cultures by vesicular stomatitis virus (VSV) effected the selective translation of viral mRNA… 
1979
1979
The activity of eukaryotic initiation factor eIF-2 in ternary complex formation with GTP and Met-tRNA.
Highly Cited
1978
Highly Cited
1978
Mode of action of the hemin-controlled inhibitor of protein synthesis.
Despite the finding that the hemin-controlled translational inhibitor in reticulocyte lysates is a cyclic AMP-independent protein… 
Highly Cited
1978
Highly Cited
1978
GTP hydrolysis during methionyl-tRNAf binding to 40 S ribosomal subunits and the site of edeine inhibition.
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