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eukaryotic translation initiation factor 2 complex location

Known as: eIF-2, eIF2, eukaryotic translation initiation factor 2 complex 
Complex of three heterogeneous polypeptide chains, that form a ternary complex with initiator methionyl-tRNA and GTP. This ternary complex binds to… Expand
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
We are just beginning to understand how translational control affects tumour initiation and malignancy. Here we use an epidermis… Expand
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Highly Cited
2005
Highly Cited
2005
Irreversible GTP hydrolysis by eIF2 is a critical step in translation initiation in eukaryotes because it is thought to commit… Expand
Highly Cited
2002
Highly Cited
2002
Environmental stress-induced phosphorylation of eIF2alpha inhibits protein translation by reducing the availability of eIF2-GTP… Expand
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Highly Cited
2000
Highly Cited
2000
Initiation of eukaryotic protein synthesis begins with the ribosome separated into its 40S and 60S subunits. The 40S subunit… Expand
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Highly Cited
2000
Highly Cited
2000
Translation initiation factor 2 (eIF2) bound to GTP transfers the initiator methionyl tRNA to the 40S ribosomal subunit. The eIF5… Expand
Highly Cited
2000
Highly Cited
2000
Phosphorylation of serine 51 residue on the alpha-subunit of eukaryotic initiation factor 2 (eIF2alpha) inhibits the guanine… Expand
Highly Cited
1999
Highly Cited
1999
In the initiation phase of eukaryotic translation, eIF5 stimulates the hydrolysis of GTP bound to eIF2 in the 40S ribosomal pre… Expand
Highly Cited
1997
Highly Cited
1997
We have isolated and characterized two suppressor genes, SUI4 and SUI5, that can initiate translation in the absence of an AUG… Expand
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Highly Cited
1989
Highly Cited
1989
All mRNAs of human immunodeficiency virus 1 (HIV-1) contain in their 5' untranslated region a sequence termed TAR that responds… Expand
Highly Cited
1982
Highly Cited
1982
There is extensive evidence that protein synthesis in reticulocyte lysates is inhibited during haem deficiency because of… Expand