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eukaryotic translation initiation factor 2 complex location

Known as: eIF-2, eIF2, eukaryotic translation initiation factor 2 complex 
Complex of three heterogeneous polypeptide chains, that form a ternary complex with initiator methionyl-tRNA and GTP. This ternary complex binds to… Expand
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
We are just beginning to understand how translational control affects tumour initiation and malignancy. Here we use an epidermis… Expand
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Highly Cited
2012
Highly Cited
2012
The delivery of Met-tRNAi to the 40S ribosomal subunit is thought to occur by way of a ternary complex (TC) comprising eIF2, GTP… Expand
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Highly Cited
2008
Highly Cited
2008
Specific interactions of the classical swine fever virus internal ribosomal entry site (IRES) with 40S ribosomal subunits and… Expand
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Highly Cited
2005
Highly Cited
2005
Irreversible GTP hydrolysis by eIF2 is a critical step in translation initiation in eukaryotes because it is thought to commit… Expand
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Highly Cited
2002
Highly Cited
2002
Environmental stress-induced phosphorylation of eIF2alpha inhibits protein translation by reducing the availability of eIF2-GTP… Expand
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Highly Cited
2000
Highly Cited
2000
Translation initiation factor 2 (eIF2) bound to GTP transfers the initiator methionyl tRNA to the 40S ribosomal subunit. The eIF5… Expand
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Highly Cited
2000
Highly Cited
2000
Phosphorylation of serine 51 residue on the alpha-subunit of eukaryotic initiation factor 2 (eIF2alpha) inhibits the guanine… Expand
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Highly Cited
1999
Highly Cited
1999
In the initiation phase of eukaryotic translation, eIF5 stimulates the hydrolysis of GTP bound to eIF2 in the 40S ribosomal pre… Expand
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Highly Cited
1998
Highly Cited
1998
The guanine nucleotide exchange activity of eIF2B plays a key regulatory role in the translation initiation phase of protein… Expand
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Highly Cited
1997
Highly Cited
1997
We have isolated and characterized two suppressor genes, SUI4 and SUI5, that can initiate translation in the absence of an AUG… Expand
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