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EIF2S1 wt Allele

Known as: EIF-2-alpha, EIF2, Eukaryotic Translation Initiation Factor 2, Subunit 1 Alpha, 35kDa wt Allele 
Human EIF2S1 wild-type allele is located in the vicinity of 14q21.3 and is approximately 27 kb in length. This allele, which encodes eukaryotic… 
National Institutes of Health

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8 relations
EIF2A geneEIF2S1 geneEIF2S3 geneEukaryotic Initiation Factor-2

Papers overview

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2020
2020
Blocking PERK resuces vascular smooth muscle cells from homocysteine-induced ER stress and apoptosis.
Hyperhomocysteinemia induces stress response in endoplasmic reticulum (ERS). Here, we tested whether blockage of homocysteine… 
2018
2018
Abstract 2742: Additional mechanisms of action of ladiratuzumab vedotin contribute to increased immune cell activation within the tumor
Ladiratuzumab vedotin (LV, SGN-LIV1A) is an antibody-drug conjugate directed against the LIV-1 protein that is currently under… 
2017
2017
Translation of Sindbis Subgenomic mRNA is Independent of eIF2, eIF2A and eIF2D
Translation of Sindbis virus subgenomic mRNA (sgmRNA) can occur after inactivation of eIF2 by phosphorylation in mammalian cells… 
2017
2017
Human Herpesvirus 6A Exhibits Restrictive Propagation with Limited Activation of the Protein Kinase R-eIF2α Stress Pathway
ABSTRACT The eIF2α protein plays a critical role in the regulation of translation. The production of double-stranded RNA (dsRNA… 
2013
2013
Crucial Roles of the Protein Kinases MK2 and MK3 in a Mouse Model of Glomerulonephritis
Elevated mitogen-activated protein kinase p38 (p38 MAPK) signaling has been implicated in various experimental and human… 
2012
2012
Refined Qingkailing Protects MCAO Mice from Endoplasmic Reticulum Stress-Induced Apoptosis with a Broad Time Window
In the current study, we are investigating effect of refined QKL on ischemia-reperfusion-induced brain injury in mice. Methods… 
2011
2011
eIF 2 A mediates translation of hepatitis C viral mRNA under stress conditions
Translation of most mRNAs is suppressed under stress conditions. Phosphorylation of the a-subunit of eukaryotic translation… 
2011
2011
Junı́n virus infection impairs stress-granule formation in Vero cells treated with arsenite via inhibition of eIF 2 a phosphorylation
Stress granules (SGs) are ephemeral cytoplasmic aggregates containing stalled translation preinitiation complexes involved in… 
2004
2004
The proteasome inhibitor , MG 132 , promotes the reprogramming of translation in C 2 C 12 myoblasts and facilitates the association of hsp 25 with the eIF 4 F complex
The eukaryotic translation initiation factor (eIF) 4E, is regulated by modulating both its phosphorylation and its availability… 
2001
2001
Expression of translation initiation factor IF2 is regulated during osteoblast differentiation
We isolated and characterized a cDNA for the N‐terminal half of the eukaryotic initiation of translation factor 2 (cIF2) during a… 
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