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etaracizumab

A humanized monoclonal IgG1 antibody directed against the vitronectin receptor alpha v beta 3 integrin. Etaracizumab blocks the binding of ligands… 
National Institutes of Health

Related topics

Related topics

10 relations

Narrower (3)

Abegrinmonoclonal antibody anti-alpha V beta 3 integrinvitaxin
Angiogenesis InhibitionEndothelium, VascularIntegrin InhibitionIntegrin alphaVbeta3

Broader (1)

Antibodies, Monoclonal, Humanized

Papers overview

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2012
2012
Comparison of FDG whole-body PET / CT and gadolinium-enhanced whole-body MRI for distant malignancies in patients with malignant tumors : a meta-analysis
that specifically binds α5β1 integrin: a phase I, pharmacokinetic, and biological correlative study. Clin Cancer Res 2008; 14… 
2010
2010
Pharmacodynamic (Phase 0) Study Using Etaracizumab in Advanced Melanoma
AlphaVbeta3 (αvβ3) is an important molecule for tumor-induced angiogenesis and is upregulated in metastatic melanoma (MM). We… 
2010
2010
Gateways to clinical trials.
Aclidinium bromide, AE-37, Alemtuzumab, AMA1-C1/ISA 720, Amlodipine besylate/atorvastatin calcium, Arachidonic acid, Arbaclofen… 
2009
2009
Combined anti-angiogenic therapy against VEGF and integrin alphabeta in an orthotopic model of ovarian cancer
Purpose: We tested the efficacy of dual targeting of vascular endothelial growth factor (VEGF) and the alphavbeta3 integrin in… 
Highly Cited
2008
Highly Cited
2008
Tumor-selective response to antibody-mediated targeting of alphavbeta3 integrin in ovarian cancer.
The alpha(v)beta(3) integrin is expressed on proliferating endothelial cells and some cancer cells, but its expression on ovarian… 
2006
2006
Gateways to clinical trials.
101M, 12B75; ABT-869, Agomelatine, Alvocidib hydrochloride, Amb a 1 ISS-1018, AMG-386, Andolast, AP-23573, Arsenic trioxide, ATI… 
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