Integrin alphaVbeta3

Known as: alphaVbeta3, Integrin, Integrin AlphaV/Beta3, Integrin alpha v beta 3 
An integrin that binds to a variety of plasma and extracellular matrix proteins containing the conserved RGD amino acid sequence and modulates cell… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
UNLABELLED The vitronectin receptor integrin alphavbeta3 promotes angiogenesis by mediating migration and proliferation of… (More)
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Highly Cited
2003
Highly Cited
2003
Expression of adhesion receptor integrin alphavbeta3 in an activated functional form strongly promotes metastasis in human breast… (More)
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Highly Cited
2002
Highly Cited
2002
The structural basis for the divalent cation-dependent binding of heterodimeric alphabeta integrins to their ligands, which… (More)
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Highly Cited
2001
Highly Cited
2001
Integrin alphavbeta3 has an important role in the proliferation, survival, invasion and migration of vascular endothelial cells… (More)
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Highly Cited
2001
Highly Cited
2001
We evaluated cellular mechanisms involved in the activation pathway of matrix prometalloproteinase-2 (pro-MMP-2), an enzyme… (More)
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Highly Cited
2001
Highly Cited
2001
Integrins are alphabeta heterodimeric receptors that mediate divalent cation-dependent cell-cell and cell-matrix adhesion through… (More)
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Highly Cited
2000
Highly Cited
2000
Angiogenesis plays a central role in the growth and metastasis of cancers. Strategies aimed at interfering with tumor blood… (More)
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Highly Cited
1999
Highly Cited
1999
Fisp12 was first identified as a secreted protein encoded by a growth factor-inducible immediate-early gene in mouse fibroblasts… (More)
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Highly Cited
1996
Highly Cited
1996
vitronectin receptor integrin ␣v␤3 and the matrix metal-In fact, we have recently shown that func-IMM24 10666 North Torrey Pines… (More)
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Highly Cited
1994
Highly Cited
1994
A single intravascular injection of a cyclic peptide or monoclonal antibody antagonist of integrin alpha v beta 3 disrupts… (More)
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