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Integrin alphaVbeta3

Known as: alphaVbeta3, Integrin, Integrin AlphaV/Beta3, Integrin alpha v beta 3 
An integrin that binds to a variety of plasma and extracellular matrix proteins containing the conserved RGD amino acid sequence and modulates cell… 
National Institutes of Health

Related topics

Related topics

24 relations
Angiogenic ProcessCell AdhesionCell Adhesion MoleculesCell-Matrix Junction

Broader (1)

Vitronectin Receptors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Efficient RGD-independent entry process of coxsackievirus A9
SummaryPreviously we showed for coxsackievirus A9 (CAV-9) that specific interactions between the RGD motif of capsid protein VP1… 
Highly Cited
2002
Highly Cited
2002
Involvement of tumor cell integrin alpha v beta 3 in hematogenous metastasis of human melanoma cells.
Early metastasis is the primary cause of death in melanoma patients. The adhesion receptor integrin alpha v beta 3 contributes to… 
2000
2000
Outside-in regulation of integrin clustering processes by ECM components per se and their involvement in actin cytoskeleton organization in a colon adenocarcinoma cell line
Abstract. We investigated in a colon adenocarcinoma cell line, the exclusive role of extracellular matrix (ECM) components in the… 
Highly Cited
1999
Highly Cited
1999
A novel beta 1 integrin-dependent mechanism of leukocyte adherence to apoptotic cells.
Adherence of leukocytes to cells undergoing apoptosis has been reported to be dependent on a variety of recognition pathways… 
1996
1996
Alpha-V/beta-3 and alpha-V/beta-5 integrin distribution in neoplastic kidney.
Integrins are transmembrane glycoproteins that mediate cell-cell and cell-matrix interactions. Altered integrin expression may… 
1994
1994
Effects of kistrin on bone resorption in vitro and serum calcium in vivo
In many cell systems, cell‐cell and cell‐matrix interactions are mediated by integrins, a family of cell surface heterodimeric… 
Highly Cited
1994
Highly Cited
1994
Building synthetic antibodies as adhesive ligands for integrins.
An antibody engineering strategy was employed to build high affinity ligands and antagonists of integrins alpha v beta 3 and… 
Highly Cited
1993
Highly Cited
1993
Spatial organization of microfilaments and vitronectin receptor, alpha v beta 3, in osteoclasts. A study using confocal laser scanning microscopy.
The primary function of the osteoclast is that of the major cell mediating bone resorption. They are actively migrating cells but… 
Highly Cited
1992
Highly Cited
1992
IL-3-dependent mast cells attach to plate-bound vitronectin. Demonstration of augmented proliferation in response to signals transduced via cell surface vitronectin receptors.
The adhesive interactions of activated mast cells with the extracellular matrix play an important role in anchorage and cellular… 
Highly Cited
1991
Highly Cited
1991
The vitronectin receptor serves as an accessory molecule for the activation of a subset of gamma/delta T cells
Constitutive production of cytokines was observed in 3 of 12 gamma/delta T cell lines derived from murine epidermis and… 
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