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Abegrin

National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
The alpha v beta 3 (αvβ3) integrin is involved in intracellular signaling regulating cell proliferation, migration, and… Expand
2010
2010
PurposeThe cell adhesion molecule integrin αvβ3 is an important player in the process of tumor angiogenesis and metastasis… Expand
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Highly Cited
2009
Highly Cited
2009
The alpha(v)beta(3)- and alpha(5)beta(1)-integrins play a key role in angiogenesis, the formation of new vessels in tissues that… Expand
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2008
2008
This study assessed the safety, immunogenicity, and pharmacokinetics of etaracizumab, a monoclonal antibody directed against the… Expand
Highly Cited
2008
Highly Cited
2008
Purpose: Abegrin is a monoclonal antibody to human integrin αVβ3, a cell adhesion molecule highly expressed on actively… Expand
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Highly Cited
2008
Highly Cited
2008
The alpha(v)beta(3) integrin is expressed on proliferating endothelial cells and some cancer cells, but its expression on ovarian… Expand
Highly Cited
2007
Highly Cited
2007
SummaryThis study assessed the safety, immunogenicity, and pharmacokinetics of etaracizumab, a monoclonal antibody directed… Expand
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Highly Cited
2006
Highly Cited
2006
Abegrin (MEDI-522 or Vitaxin), a humanized monoclonal antibody against human integrin alpha(v)beta(3), is in clinical trials for… Expand
2006
2006
The humanized monoclonal antibody Abegrin, currently in phase II trials for treatment of solid tumors, specifically recognizes… Expand
Highly Cited
2006
Highly Cited
2006
Abegrin (MEDI-522 or Vitaxin), a humanized monoclonal antibody against human integrin alpha(v)beta(3), is in clinical trials for… Expand