Abegrin

 
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
BACKGROUND The alpha (v) beta (3) (alpha(v)beta(3)) integrin is involved in intracellular signaling regulating cell proliferation… (More)
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2010
2010
The cell adhesion molecule integrin αvβ3 is an important player in the process of tumor angiogenesis and metastasis. Abegrin™, a… (More)
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Highly Cited
2009
Highly Cited
2009
The alpha(v)beta(3)- and alpha(5)beta(1)-integrins play a key role in angiogenesis, the formation of new vessels in tissues that… (More)
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2008
2008
This study assessed the safety, immunogenicity, and pharmacokinetics of etaracizumab, a monoclonal antibody directed against the… (More)
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2008
2008
The alpha(v)beta(3) integrin is expressed on proliferating endothelial cells and some cancer cells, but its expression on ovarian… (More)
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2008
2008
PURPOSE Abegrin is a monoclonal antibody to human integrin alphavbeta3, a cell adhesion molecule highly expressed on actively… (More)
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2007
2007
This study assessed the safety, immunogenicity, and pharmacokinetics of etaracizumab, a monoclonal antibody directed against the… (More)
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2007
2007
New research, including a phase II clinical trial in advanced melanoma, is adding to growing evidence that slowing metastasis may… (More)
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2006
2006
Abegrin (MEDI-522 or Vitaxin), a humanized monoclonal antibody against human integrin alpha(v)beta(3), is in clinical trials for… (More)
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2006
2006
The humanized monoclonal antibody Abegrin, currently in phase II trials for treatment of solid tumors, specifically recognizes… (More)
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