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eritoran

Known as: 3-O-decyl-2-deoxy-6-O-(2-deoxy-3-O-(3-methoxydecyl)-6-O-methyl-2-((1-oxo-11-octadecenyl)amino)-4-O-phosphonoglucopyranosyl)-2-((1,3-dioxotetradecyl)amino)-1-(dihydroxy phosphate)glucopyranose 
 
National Institutes of Health

Papers overview

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2016
2016
Colorectal carcinogenesis is affected by overexpression of the lipopolysaccharide (LPS) receptors CD14 and TLR4, which antagonize… Expand
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Highly Cited
2013
Highly Cited
2013
There is a pressing need to develop alternatives to annual influenza vaccines and antiviral agents licensed for mitigating… Expand
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Review
2013
Review
2013
Toll-like receptors (TLRs) are pattern recognition receptors playing a fundamental role in sensing microbial invasion and… Expand
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Highly Cited
2011
Highly Cited
2011
Infectious complications resulting from resection of colorectal cancer (CRC) elevates the risk of cancer recurrence and… Expand
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2011
2011
AIMS Toll-like receptor 4 (TLR4) recognizes lipopolysaccharides and endogenous ligands released after organ injury. Deficiency of… Expand
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2010
2010
BACKGROUND Ischemia-reperfusion injury (I/R) has a negative effect on renal allograft survival. Using a rat model of kidney IR… Expand
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Review
2010
Review
2010
Despite a decrease in mortality over the last decade, sepsis remains the tenth leading causes of death in western countries and… Expand
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Highly Cited
2007
Highly Cited
2007
TLR4 and MD-2 form a heterodimer that recognizes LPS (lipopolysaccharide) from Gram-negative bacteria. Eritoran is an analog of… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND We previously reported that the functional mutation of Toll-like receptor 4 (TLR4) in C3H/HeJ mice subjected to… Expand
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2004
2004
Eritoran, a structural analogue of the lipid A portion of lipopolysaccharide (LPS), is an antagonist of LPS in animal and human… Expand
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