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eritoran

Known as: 3-O-decyl-2-deoxy-6-O-(2-deoxy-3-O-(3-methoxydecyl)-6-O-methyl-2-((1-oxo-11-octadecenyl)amino)-4-O-phosphonoglucopyranosyl)-2-((1,3-dioxotetradecyl)amino)-1-(dihydroxy phosphate)glucopyranose 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

DisaccharidesSugar Phosphates
E5564

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Using multiple 'omics strategies for novel therapies in sepsis
2018
2018
Behavioral effects of toll-like receptor-4 antagonist ‘eritoran’ in an experimental model of depression: role of prefrontal and hippocampal neurogenesis and &ggr;-aminobutyric acid/glutamate balance
Depression is the disease of the modern era. The lack of response to the available antidepressants, which were developed on the… 
2017
2017
Antagonizing LPS-Induced Dimerization
Review
2014
Review
2014
What's new in the quagmire of sepsis?
2014
2014
Effect of the Toll-Like Receptor 4 Antagonist Eritoran on Retinochoroidal Inflammatory Damage in a Rat Model of Endotoxin-Induced Inflammation
Purpose. We investigated the effect of eritoran, a Toll-like receptor 4 antagonist, on retinochoroidal inflammatory damage in an… 
Review
2013
Review
2013
Three-dimensional mapping of differential amino acids of human, murine, canine and equine TLR4/MD-2 receptor complexes conferring endotoxic activation by lipid A, antagonism by Eritoran and species…
A literature review concerning the unexpected species differences of the vertebrate innate immune response to lipid IVA was… 
2013
2013
Eritoran insight for influenza treatment
A University of Maryland team has used a toll-like receptor 4 antagonist to treat influenza in mice. The results provide a… 
2012
2012
Deactivation of the lipopolysaccharide antagonist eritoran (E5564) by high-density lipoprotein-associated apolipoproteins
Lipid A, the active moiety of LPS, exerts its effects through interaction with TLR4, triggering a signalling cascade that results… 
2007
2007
Influence of Plasma Cholesterol and Triglyceride Concentrations and Eritoran (E5564) Micelle Size on its Plasma Pharmacokinetics and Ex Vivo Activity Following Single Intravenous Bolus Dose Into…
PurposeEritoran (E5564) is a glycophospholipid that acts as a toll-like receptor 4 (TLR4) antagonist that is being tested as a… 
Highly Cited
2006
Highly Cited
2006
E5564 (Eritoran) inhibits lipopolysaccharide-induced cytokine production in human blood monocytes
Abstract.Objective and designIn this ex vivo laboratory study, we investigated the effects of E5564 (eritoran), a toll-like… 
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