FAQ

ergosterol biosynthetic process

Known as: ergosterol anabolism, ergosterol formation, ergosterol synthesis 
The chemical reactions and pathways resulting in the formation of ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast… (More)

Topic mentions per year

Topic mentions per year

1948-2017
05101519482016

Papers overview

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Highly Cited
2008
Highly Cited
2008
A gain-of-function mutation in the transcription factor Upc2p causes upregulation of ergosterol biosynthesis genes and increased fluconazole resistance in a clinical Candida albicans isolate.
In the pathogenic yeast Candida albicans, the zinc cluster transcription factor Upc2p has been shown to regulate the expression… (More)
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2004
2004
A yeast strain lacking lipid particles bears a defect in ergosterol formation.
Lipid particles of the yeast Saccharomyces cerevisiae are storage compartments for triacylglycerols (TAG) and steryl esters (STE… (More)
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2004
2004
Genomic approach to identification of mutations affecting caspofungin susceptibility in Saccharomyces cerevisiae.
The antifungal agent caspofungin (CAS) specifically interferes with glucan synthesis and cell wall formation. To further study… (More)
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2003
2003
Disruption of ergosterol biosynthesis confers resistance to amphotericin B in Candida lusitaniae.
Candida lusitaniae is an emerging human pathogen that, unlike other fungal pathogens, frequently develops resistance to the… (More)
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Highly Cited
1999
Highly Cited
1999
Quantitation of ergosterol content: novel method for determination of fluconazole susceptibility of Candida albicans.
MIC end points for the most commonly prescribed azole antifungal drug, fluconazole, can be difficult to determine because its… (More)
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1998
1998
Production of the carotenoids lycopene, beta-carotene, and astaxanthin in the food yeast Candida utilis.
The food-grade yeast Candida utilis has been engineered to confer a novel biosynthetic pathway for the production of carotenoids… (More)
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1996
1996
Cloning and characterization of the Saccharomyces cerevisiae C-22 sterol desaturase gene, encoding a second cytochrome P-450 involved in ergosterol biosynthesis.
The ERG5 gene from Saccharomyces cerevisiae was cloned by complementation of an erg5-1 mutation using a negative selection… (More)
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1994
1994
The identification of a gene family in the Saccharomyces cerevisiae ergosterol biosynthesis pathway.
The Saccharomyces cerevisiae ERG24 gene, encoding sterol delta 14 reductase (Erg24p), was cloned by selecting strains carrying… (More)
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1991
1991
Cloning, disruption and sequence of the gene encoding yeast C-5 sterol desaturase.
The ERG3 gene from Saccharomyces cerevisiae has been cloned by complementation of an erg3-2 mutation. ERG3 is the putative gene… (More)
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1990
1990
Ultrastructural alterations induced by two ergosterol biosynthesis inhibitors, ketoconazole and terbinafine, on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi.
We report the ultrastructural alterations induced during the proliferative stages of Trypanosoma (Schizotrypanum) cruzi, the… (More)
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