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ergosterol biosynthetic process

Known as: ergosterol anabolism, ergosterol formation, ergosterol synthesis 
The chemical reactions and pathways resulting in the formation of ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast… 
National Institutes of Health

Related topics

Related topics

1 relation
positive regulation of ergosterol biosynthetic process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
A Role for Sterol Levels in Oxygen Sensing in Saccharomyces cerevisiae
Upc2p and Ecm22p are a pair of transcription factors responsible for the basal and induced expression of genes encoding enzymes… 
Highly Cited
1999
Highly Cited
1999
PDR16 and PDR17, Two Homologous Genes ofSaccharomyces cerevisiae, Affect Lipid Biosynthesis and Resistance to Multiple Drugs*
The Saccharomyces cerevisiae open reading frame YNL231C was recently found to be controlled by the multiple drug resistance… 
Highly Cited
1996
Highly Cited
1996
Cloning and characterization of the Saccharomyces cerevisiae C-22 sterol desaturase gene, encoding a second cytochrome P-450 involved in ergosterol biosynthesis.
Highly Cited
1991
Highly Cited
1991
Cloning and characterization of ERG8, an essential gene of Saccharomyces cerevisiae that encodes phosphomevalonate kinase
Saccharomyces cerevisiae strains that contain the ery8-1 mutation are temperature sensitive for growth due to a defect in… 
Highly Cited
1990
Highly Cited
1990
In vivo effects of fenpropimorph on the yeast Saccharomyces cerevisiae and determination of the molecular basis of the antifungal property
The effects of fenpropimorph on sterol biosynthesis and growth of Saccharomyces cerevisiae were examined to pinpoint the mode of… 
Review
1987
Review
1987
Anti-Candida drugs--the biochemical basis for their activity.
The past years have seen a continuous effort toward the synthesis of new antifungal agents. Most of them belong to the N… 
Highly Cited
1987
Highly Cited
1987
Effect of antifungal agents on lipid biosynthesis and membrane integrity in Candida albicans
Eight antifungal agents were examined for effects on lipid biosynthesis and membrane integrity in Candida albicans. Lipids were… 
Highly Cited
1986
Highly Cited
1986
Ergosterol biosynthesis inhibition by the thiocarbamate antifungal agents tolnaftate and tolciclate
The thiocarbamate antimycotics tolnaftate and tolciclate blocked sterol biosynthesis in fungal cells and cell extracts, with… 
Review
1985
Review
1985
Biochemical targets for antifungal azole derivatives: hypothesis on the mode of action.
The selective interaction of low concentrations of azole derivatives and other nitrogen heterocycles with cytochrome P-450 may be… 
Highly Cited
1978
Highly Cited
1978
Biochemical effects of miconazole on fungi. II. Inhibition of ergosterol biosynthesis in Candida albicans.
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