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elmustine

Known as: 1-(2-Chloroethyl)-3-(2-hydroxyethyl)-1-nitrosourea, 1-Nitroso-1-chloroethyl-3-hydroxyethylurea, 2-chloroethyl-1-nitrosureidoethanol 
A (2-chloroethy1)nitrosourea derivative related to carmustine, with antineoplastic activity.
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

MutagensNitrosourea Compounds

Narrower (1)

NSC 29485

Papers overview

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2009
2009
Towards a study opportunities recommender system in ontological principles-based on semantic web environment
A professional career selection is a complicated process for university student candidates and often little technical tolls are… 
1992
1992
Genomic differences between O6-methylguanine-DNA methyltransferase proficient (Mex+) and deficient (Mex-) cell lines: possible role of genetic and epigenetic changes in conversion of Mex+ into Mex-.
1991
1991
In vitro investigations on the antineoplastic effect of hexadecylphosphocholine.
The in vitro antineoplastic activity of hexadecylphosphocholine (HPC, CAS 58066-85-6) on methylnitrosourea (MNU)-induced mammary… 
Highly Cited
1988
Highly Cited
1988
Glutathione reductase inhibitors as potential antimalarial drugs. Effects of nitrosoureas on Plasmodium falciparum in vitro.
1988
1988
Glutathione reductase-deficient erythrocytes as host cells of malarial parasites.
1987
1987
A method to determine the carbamoylating potential of 1-(2-chloroethyl)-1-nitrosoureas.
1-(2-Chloroethyl)-1-nitrosoureas (CNUs) are alkylating agents that also possess carbamoylating activity, depending on the… 
1984
1984
DNA damage and repair in the bone marrow of rats treated with four chloroethylnitrosoureas.
DNA is considered to be an important target for the antitumor and toxic properties of the chloroethylnitrosoureas. Since the main… 
1979
1979
Examination of four newly synthesized 2-chloroethylnitrosoureas in comparison with BCNU, CCNU, MeCCNU, chlorozotocin and hydroxyethyl-CNU in preterminal rat leukemia L 5222
SummaryThe newly synthesized nitrosoureas 1-(2-chloroethyl)-1-nitroso-3-(methylenecarboxamido)-urea (Acetamido-CNU), 1-(2… 
1978
1978
Chemotherapeutic activity of new 2-chloroethylnitrosoureas in rat L5222 leukemia: comparison of bifunctional and water-soluble derivatives with 1,3-bis(2-chloroethyl)-1-nitrosourea.
The chemotherapeutic activity of eight nitrosourea derivatives was compared with that of 1,3-bis(2-chloroethyl)-1-nitrosourea… 
1976
1976
Some new congeners of the anticancer agent 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) synthesis of bifunctional analogs and water soluble derivatives and preliminary evaluation of their…
The synthesis of new analogs of the anticancer agent BCNU is described. It involves the preparation of N-(2-chloroethyl)-N… 
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